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Activity Number: 412
Type: Topic Contributed
Date/Time: Wednesday, August 1, 2007 : 10:30 AM to 12:20 PM
Sponsor: Section on Nonparametric Statistics
Abstract - #308845
Title: Generalized Semiparametric Linear Mixed Effects Models
Author(s): Tatiyana Apanasovich*+
Companies: Cornell University
Address: 228 Rhodes Hall, Ithaca, NY, 14850,
Keywords:
Abstract:

Generalized linear mixed effects models are widely used for longitudinal non-Gaussian data analysis to incorporate between-subject and within-subject variations. To weaken model assumption for possible misspecification and to avoid the curse of dimensionality of fully nonparametric regression in the presence of several predictor variables, semiparametric models have been considered. We employ the penalized likelihood regression to estimate the models. We will focus on the efficient computation and the effective smoothing parameter selection. Real-data examples from AIDS studies will be presented to demonstrate the applications of the methodology.


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Revised September, 2007