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Activity Number: 92
Type: Topic Contributed
Date/Time: Monday, July 30, 2007 : 8:30 AM to 10:20 AM
Sponsor: Section on Health Policy Statistics
Abstract - #308423
Title: Is Newer Always Better? Re-evaluating the Benefits of Newer Pharmaceuticals
Author(s): Michael Law*+ and Karen Grépin
Companies: Harvard Medical School/Harvard Pilgrim HealthCare and Harvard University
Address: 133 Brookline Ave, Boston, MA, 02215,
Keywords: Prescription Drugs ; Propensity Score Matching ; Drug Offsets ; Health Care Costs
Abstract:

Whether newer pharmaceuticals justify their higher cost by "offsetting" other health spending (such as hospital services) is an important health policy question. We aimed to replicate a previous analysis which suggests the savings from newer drugs substantially outweigh their additional cost. We find the results are highly dependent on the model and dataset used: substituting either a model less sensitive to outliers or a newer data release results in the effect disappearing; substituting both causes it to reverse in direction. Further, we propose an alternative model using propensity score matching and a two-part expenditure model, which we estimate for hypertension. We find using a newer drug is associated with $179 higher annual drug costs, but the change in non-drug spending is indistinguishable from zero. Thus, we find no evidence of offsets from these medications.


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Revised September, 2007