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Activity Number:
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67
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Type:
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Contributed
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Date/Time:
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Sunday, July 29, 2007 : 4:00 PM to 5:50 PM
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Sponsor:
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ENAR
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| Abstract - #308322 |
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Title:
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Design and Analysis of Multiple Control Arm Studies
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Author(s):
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Laura Johnson*+ and Catherine M. Stoney
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Companies:
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National Institutes of Health and National Institutes of Health
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Address:
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NCCAM, 6707 Democracy Blvd, Bethesda, MD, 20892-5475,
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Keywords:
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mixed models ; control groups ; placebo ; research design
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Abstract:
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Placebo controlled studies are often considered impossible or unethical for certain populations and topics under study. Thus, alternative treatment or other control groups are often included in designs to better characterize the effects of experimental treatments. However, it is clear from specific investigation of placebo responding that the placebo response plays a measurable role in clinical research. How and which control groups are included in experimental designs greatly influences choice of analysis and what information can be ultimately derived from the analyses. We will focus on different types of control groups, limitations and advantages of placebo control groups, why more than one control group may be needed in a study even when not dismantling a complex intervention, and how choice of analysis model can give different insights into the same study.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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