JSM Preliminary Online Program
This is the preliminary program for the 2007 Joint Statistical Meetings in Salt Lake City, Utah.

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Activity Number: 223
Type: Invited
Date/Time: Tuesday, July 31, 2007 : 8:30 AM to 10:20 AM
Sponsor: Biopharmaceutical Section
Abstract - #307940
Title: Toxicogenomics for Toxicity Evaluation and Biomarker Identification
Author(s): Hisham Hamadeh*+
Companies: Amgen Inc.
Address: One Amgen Center Dr, Thousand Oaks, CA, 91320,
Keywords: toxicity ; toxicogenomics ; biomarker ; microarrays
Abstract:

The use of genomic resources to aid in toxicity evaluation is gaining more acceptance and interest within academic, governmental, and industrial settings. Attributing transcript, protein, or metabolite fluctuations as associations with, or precursors to, toxicity outcomes has been challenging. Various strategies will be presented aimed at delineating specific and sensitive toxicity-related fluctuations in transcripts, proteins, or metabolites. The discussion will extend to the identification of potential biomarkers that may be used for predictive or diagnostic purposes.

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Revised September, 2007