JSM 2004 - Toronto

Abstract #301501

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Activity Number: 307
Type: Contributed
Date/Time: Wednesday, August 11, 2004 : 8:30 AM to 10:20 AM
Sponsor: Biopharmaceutical Section
Abstract - #301501
Title: On Selecting among Treatments with Binomial Outcomes
Author(s): Elena M. Buzaianu*+ and Pinyuen Chen
Companies: Syracuse University and Syracuse University
Address: 215 Carnegie Hall, Syracuse, NY, 13210,
Keywords: selection ; binomial ; least favorable configuration
Abstract:

Most of the procedures for selecting one of the best among several treatments under the binomial settings are based on applying the normal theory to the discrete data. Consequently, such procedures may not be safely applied when dealing with small sample sizes. This paper considers the LFCs for the exact versions of those procedures. That is, procedures that are based on the binomial distributions instead of their approximations. We begin with the procedure proposed by Sobel and Hyuett, which does not involve a control. Then we consider the single stage procedure by Dunnet and a two-stage procedure by Thall, Simmon, and Ellenberg, where a control is involved. With our results, the redefined procedures can be applied to any sample size.


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