JSM 2004 - Toronto

Abstract #301491

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Activity Number: 230
Type: Contributed
Date/Time: Tuesday, August 10, 2004 : 10:30 AM to 12:20 PM
Sponsor: IMS
Abstract - #301491
Title: Efficient Cross-over Designs for Comparing Test Treatments with a Control Treatment
Author(s): Min Yang*+
Companies: University of Nebraska, Lincoln
Address: 103 Miller Hall, Lincoln, NE, 68583-0712,
Keywords: cross-over design ; repeated measurements ; treatments vs. a control ; A-optimality ; carryover effects
Abstract:

Comparing t test treatments with one control treatment in cross-over design is considered when the number of periods is less than number of treatments t+1. The currently available result is constructing such designs in a restricted class, i.e., no treatment is allowed to follow itself and the control treatment is uniform in periods. We will present a new result to construct A-optimal designs for some parameters under a much less restricted class, i.e., treatment is allowed to be immediately followed by itself. It also showed that the currently available designs are highly efficient under nearly whole class for those parameters.

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Revised March 2004