JSM 2004 - Toronto

Abstract #301115

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Activity Number: 17
Type: Topic Contributed
Date/Time: Sunday, August 8, 2004 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #301115
Title: Interaction between BMI and Diabetes in Modeling Mortality
Author(s): Robert G. Fowler*+
Companies: Florida State University
Address: PO Box 15526, Tallahassee, FL, 32317,
Keywords: Cox-model ; meta-analysis ; BMI ; diabetes
Abstract:

This paper investigates the interaction between BMI and diabetes. It is known that both incidence of diabetes and greater BMI increases the relative risk of mortality for most causes of death. Preliminary investigation shows that this interaction is present in several studies and absent in others. Estimates of the relative risk associated with this interaction are calculated using Cox proportional hazard models. The individual-level data for these models is from the diverse population dataset of 27 medical studies that has been compiled at Florida State University. Meta-analysis is used to summarize the differing results from the proportional hazard models. The presence of a BMI-diabetes interaction indicates weight is a greater risk factor for diabetics in comparison to nondiabetics.


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