JSM 2004 - Toronto

Abstract #300089

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Activity Number: 419
Type: Invited
Date/Time: Thursday, August 12, 2004 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract - #300089
Title: Computational Strategies for Analyzing Protein Interaction Networks
Author(s): George Michailidis*+
Companies: University of Michigan
Address: 439 West Hall, Ann Arbor, MI, 48109-1092,
Keywords: protein interactions ; graph theory ; data integration
Abstract:

Advances in high-throughput proteomics techniques, such as yeast > two-hybrid system, have produced a rapidly expanding volume of protein interaction data. We use a graph theoretic approach to discuss models that integrate protein interaction information from different experimental sources in order to produce a complete interaction network. Furthermore, we develop algorithms that aid in the identification of protein complexes.

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Revised March 2004