Keyword Search
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Keyword Search Criteria: Design returned 290 record(s)
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Sunday, 07/29/2018
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Bayesian Nonparametric Hierarchical Models for Lightcurve Classification and Observation Decisions
David Edward Jones, Duke University and SAMSI; Sujit Ghosh, North Carolina State Univ.; Ana-Maria Staicu, NC State University; Ashish Mahabal, Caltech
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Gaussian Process Regression with Large Data Sets: Has the Problem Been Solved?
Sonja Surjanovic, University of British Columbia; William Welch, University of British Columbia
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The Analysis of Means in the Presence of Covariate (ANOMC)
Tahir Mahmood, City University of Hong Kong; Min Xie, City University of Hong Kong; Muhammad Riaz, King Fahd University of Petroleum and Minerals
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Measurement Reliability in Mental Health Research: Critical Implications for Research Design and Analysis
Alessandro De Nadai, Texas State University; Marieke Visser, Texas State University
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Repeated-Measures ANCOVA for an Antibiotic-Free Experiment in Swine
Danielle Wilson-Wells, DNA Genetics; Tom A. Rathje, DNA Genetics; Caitlyn E Bruns, DNA Genetics
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Estimation in the Nested Case-Control Design Under Model Misspecification
Michelle Nuno; Daniel L. Gillen, University of California, Irvine
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Retrospective Study Designs for Longitudinal Data Obtained from a Biobank-Linked Electronic Medical Record
Jonathan Schildcrout, Vanderbilt University Medical Center
2:05 PM
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Model Calibration of a Protein-Signaling Network
Derek Bingham, Simon Fraser University; David Alexander Campbell, Simon Fraser University; David C. Clarke, Simon Fraser University; Mike Grosskopf, Simon Fraser University; Luyao Lin, Simon Fraser University; Biljana Jonoska Stojkova , University of British Columbia
2:05 PM
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Methods for Estimating Trend in Indicators Monitored with Complex Survey Designs
Leigh Starcevich, Western EcoSystems Technology Inc. (WEST)
2:05 PM
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Application of Propensity Score Quintile Matching for Baseline Parameters in a Medical Device Trial Design
Hong Wang, Boston Scientific Corporation; Songtao Jiang, Boston Scientific; Peter Lam, Boston Scientific
2:05 PM
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Probability-Proportional-To-Size Ranked Set Sampling from Stratified Populations
Omer Ozturk, Ohio State University
2:05 PM
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Measurement Reliability in Mental Health Research: Critical Implications for Research Design and Analysis
Alessandro De Nadai, Texas State University; Marieke Visser, Texas State University
2:15 PM
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Dosing Designs for Bayesian Emax Models
Neal Thomas, Pfizer
2:25 PM
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Designing Trials Using Bayesian Methods with Historical Controls
Michael Sonksen, Eli Lilly and Company
2:25 PM
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Repeated-Measures ANCOVA for an Antibiotic-Free Experiment in Swine
Danielle Wilson-Wells, DNA Genetics; Tom A. Rathje, DNA Genetics; Caitlyn E Bruns, DNA Genetics
2:35 PM
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A Sampling Design for an Ordered Population
Xiaofei Zhang, Iowa State Univ; Wayne Fuller, Iowa State University
2:35 PM
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Estimation in the Nested Case-Control Design Under Model Misspecification
Michelle Nuno; Daniel L. Gillen, University of California, Irvine
2:35 PM
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Statistics at Consumer Reports
Michael Saccucci, Consumer Reports
2:45 PM
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Dose Selection Using Nonlinear Mixed-Effect Model Averaging Approaches in Conjunction with Adaptive Optimal Design Techniques
Andrew Hooker, Uppsala Universitet
2:45 PM
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Statistical Considerations in Cervical Screening Cytology Device Evaluation
Xiaoqin Xiong, Food and Drug Administration
2:50 PM
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Enhancement of Transparency, Reproducibility, and Replicability in the Integration of Multiple Data Sources
John L. Eltinge, United States Census Bureau
2:55 PM
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Current Population Survey State GVFs and Design Effects
Tamara Zimmerman, Bureau of Labor Statistics; Edwin Robison, Bureau of Labor Statistics
3:05 PM
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The Analysis of Means in the Presence of Covariate (ANOMC)
Tahir Mahmood, City University of Hong Kong; Min Xie, City University of Hong Kong; Muhammad Riaz, King Fahd University of Petroleum and Minerals
3:20 PM
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Dealing with Inaccurate Measures of Size in Two-Stage Probability Proportional to Size Sample Designs: Applications in African Household Surveys
Graham Kalton, Westat; Ismael Flores Cervantes, Westat; Carlos Arieira, Westat; Mike Kwanisai, Westat; Jehun Kim, Westat; Elizabeth Radin, ICAP at Columbia University; Suzue Saito, ICAP at Columbia University; Anindya De, U.S. Centers for Disease Control and Prevention; Stephen McCracken, U.S. Centers for Disease Control and Prevention; Paul Stupp, U.S. Centers for Disease Control and Prevention
3:20 PM
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Nonparametric Analyses of Longitudinal Perturbation Data from the Human Microbiome
Susan Holmes, Statistics
4:05 PM
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New Developments with the Sequential Parallel Comparison Design
Gheorghe Doros, Boston University; Denis Rybin, Pfizer, Inc
4:05 PM
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Two Tales from A/B Testing: The M Error and Partial Identification in Factorial Designs
Jiannan Lu, Microsoft; Yixuan Qiu, Purdue University; Alex Deng, Microsoft Corporation
4:05 PM
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Adaptively-Tuned Particle Swarm Optimization with Application to Spatial Design
Matthew Simpson, University of Missouri; Christopher K. Wikle, University of Missouri; Scott H. Holan, University of Missouri/U.S. Census Bureau
4:05 PM
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Helping New Healthcare Researchers to Consider Statistics Early
Nicole Herrera, Children's National Medical Center; Heather Gordish-Dressman, Children's National Medical Center; James Bost, Children's National Medical Center
4:05 PM
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A Non-Response and Measurement Error Analysis for the National Survey of College Graduates
Kayla Varela, U.S. Census Bureau; Allison Zotti, U.S. Census Bureau; Kevin Tolliver, U.S. Census Bureau; Amanda Nagle, U.S. Census Bureau
4:05 PM
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A Gate-Keeping Test for Selecting Adaptive Interventions for Depression Management Under General SMART Designs
Xiaobo Zhong, Columbia University; Bin Cheng, Columbia University; Min Qian, Columbia University; Ying Kuen Ken Cheung, Columbia University
4:20 PM
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Implementation of Adaptive Design on the Medicare Current Beneficiary Survey
Christopher Ward, NORC at the University of Chicago; Felicia LeClere, NORC at the University of Chicago; Kari Carris, NORC at the University of Chicago; Stephen Cohen, NORC at the University of Chicago; Dean Resnick, NORC; Micah Sjoblom, NORC at the University of Chicago; Jennifer Vanicek, NORC at the University of Chicago; Ying Li, NORC at the University of Chicago
4:20 PM
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Design and Analysis of Survival Trials with Treatment Crossover
Xiaodong Luo, Sanofi
4:25 PM
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The Importance of Statistics in Distinguishing Opinion, Relevance, and Demonstrably Sufficient Science
Karen Kafadar, University of Virginia
4:30 PM
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Adaptive Design in the National Immunization Survey-Teen Provider Record Check Phase
Xian Tao, NORC at the University of Chicago; Megha Revanam, NORC at the University of Chicago; Benjamin Skalland, NORC at the University of Chicago; Kirk Wolter, NORC at the University of Chicago; David Yankey, Centers for Disease Control and Prevention; Zhen Zhao, CDC; Kennon Copeland, NORC at the University of Chicago
4:35 PM
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Two-Stage Enrichment Clinical Trial Design with Adjustment for Misclassification in Predictive Biomarkers
Yong Lin, Rutgers, The State University of New Jersey; Weichung Joe Shih, Rutgers University; Shou-En Lu, Rutgers University
4:35 PM
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Optimal Designs for Comparison of Response Surfaces
Mong-Na Lo Huang, National Sun Yat-Sen University; Tzu-Lung Yuan, National Sun Yat-sen University; Chi-Hsiang Chu, Kaohsiung Chang Gung Memorial Hospital
4:35 PM
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Variance Components Estimators OPE, NOPE and AOPE in Linear Mixed Effects Models
Subir Ghosh, Univ. of California, Riverside
4:35 PM
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Using Delayed Start Design and Analysis to Investigate Potential Disease Modifying Effects in Alzheimer's Disease
Hong Liu-Seifert, Eli Lilly and Company; Scott Andersen, Eli Lilly and Company
4:45 PM
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Multiple Imputation of Missing Income Data for the Redesigned National Health Interview Survey
Guangyu Zhang, National Center for Health Statistics; Yulei He, CDC/NCHS; Pavlina Rumcheva, National Center for Health Statistics ; Aaron Maitland, National Center for Health Statistics ; Suresh Srinivasan, National Center for Health Statistics ; Alain Moluh, NCHS; Matthew Bramlett, NCHS; Chris Moriarity, National Center for Health Statistics; Tina Norris, NCHS
4:45 PM
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Sample Size and Power Analysis for RNA-Seq Differential Expression in Paired Study Designs
Masha Kocherginsky, Northwestern University; Kwang-Youn Kim, Northwestern University ; Daniela E Matei, Northwestern University
4:45 PM
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Inference and Optimal Design for Longitudinal Cluster-Randomized Clinical Trials Given a Small Number of Clusters with Application to a Serious Mental Illness Intervention Study
CHAE RYON KANG, University of Pittsburgh; DI ZHANG, University of Pittsburgh
4:50 PM
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Developing Seamless Tools to Support Metrics for Adaptive Survey Designs
Stephen Cohen, NORC at the University of Chicago; Imad Lakhal, NORC; Zachary H Seeskin, NORC at the University of Chicago; Dean Resnick, NORC
4:50 PM
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Quantifying and Controlling for Sources of Technical Variation and Bias in Longitudinal Microbiome Surveys
Justin D Silverman, Duke University; Heather Durand, Duke University; Sayan Mukherjee, Duke University; Lawrence A David, Duke University
5:05 PM
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Side Effect Reduction of Prior and Processed Information on Survey Design
Abdellatif Demnati, Independent Researcher
5:05 PM
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Design and Analysis of Cancer Immunotherapy Trials with Potential Violation of Proportional Hazards Assumption
Xiaofei Wang, Duke University School of Medicine; Guangyu Yang , University of Michigan
5:05 PM
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Budget-Constrained Group Testing Designs for Prevalence Estimation
Shih-Hao Huang, Academia Sinica
5:05 PM
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An Approach to Predict Final Yield Among Interim Cases
Rui Jiao, Westat; Andrea Piesse, Westat
5:20 PM
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Monday, 07/30/2018
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Strengthening Partnerships in Community-Based Participatory Research by Demystifying Experimental Design and Statistical Analysis
Thomas Belin, UCLA
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What If We Get a Break in Series? Risk Management in the Integration of Multiple Data Sources
John L. Eltinge, United States Census Bureau
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Global Sensitivity Analysis from Given Data : Elementary Effect Approach
Jong hyun Kim, Hanyang University; Dae il Jang, Hanyang University; Kyung joon Cha, Hanyang University
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SOLID: Sequential Optimization of Locally Important Dimensions
Munir Winkel, North Carolina State University; Brian Reich, North Carolina State University; Jonathan Stallings, North Carolina State University; Curtis Storlie, Mayo Clinic
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Optimal Sampling Regime for Estimating Population Dynamics
Rebecca Bergee; Edward L Boone, Virginia Commonwealth University; Ryad Ghanam, Virginia Commonwealth University
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Assessing Treatment Benefit in Patient-Centric Study Designs
Jagadish Gogate, Johnson & Johnson-Janssen R&D
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Embedding Observational Studies into Hypothetical Fractional-Factorial Experiments
Nicole Pashley, Harvard University; Marie-Abele Bind, Harvard University
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Statistically Supporting Health Policy Decision-Making
Frank Yoon, IBM Watson Health
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Efficient Design and Analysis of Cluster Randomized Trials
Hengshi Yu, University of Michigan, Ann Arbor; Fan Li, Duke Univeristy; John A. Gallis, Duke University; Elizabeth L. Turner, Duke Global Health Institutes
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Using Modified Competitive Swarm Optimizer to Find D-Optimal Designs for Complicated Logistic Models
Zizhao Zhang, UCLA; Weng Kee Wong, UCLA
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Uncertainty in the Design Stage of Two-Stage Bayesian Propensity Score Analysis
Shirley Liao
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Assessing Health Care Interventions via an Interrupted Time Series Model: Study Power and Design Considerations
Maricela Cruz, University of California, Irvine; Miriam Bender, University of California, Irvine; Daniel L. Gillen, University of California, Irvine; Hernando Ombao, King Abdullah University of Science and Technology
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A DCp Criterion for Nonparametric First Derivative Estimation
Sisheng Liu, Fred Hutchinson Cancer Research Center; Richard Charnigo, University of Kentucky; Cidambi Srinivasan, University of Kentucky
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A Comparison of Modeling Approaches for Stepped-Wedge Cluster Randomized Trials That Include Multilevel Clustering, Confounding by Time, and Effect Modification
Lance Ford, University of Oklahoma Health Sciences Center; Julie A Stoner, University of Oklahoma Health Sciences Center; Daniel Zhao, OU Health Sciences Center; Tabitha Garwe, University of Oklahoma Health Sciences Center; Ann Chou, University of Oklahoma Health Sciences Center; Daniel Duffy, University of Oklahoma-Tulsa
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Helping All Students Properly Design and Analyze Experiments
Jennifer Broatch, Arizona State University
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Leveraging Multiple Study Designs and Statistical Methods to Evaluate Comparative Effectiveness of Asthma Medications
Tebeb Gebretsadik, Vanderbilt University Medical Center; Pingsheng Wu, Vanderbilt University; Rees L Lee, U. S. Navy; Amber M Evans, Health ResearchTX LLC; Tan Ding, Vanderbilt University Medical Center; Nicholas M Sicignano, Health Research Tx ; Ann Wu, Harvard Medical School; Carlos Iribarren, Kaiser Permanente Division of Research; Butler Melissa, Kaiser Permanente; Chang Yu, Vanderbilt University Medical Center; William Dupont, Vanderbilt University Medical Center; Christina Fox, Health ResearchTx; Tina V Hartert, Vanderbilt University Medical Center
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Basket Trial Design Using Bayesian Model Averaging
Matthew Psioda, University of North Carolina; Jiawei Xu, University of North Carolina; Qi Jiang, Amgen; Chunlei Ke, Biogen; Zhao Yang, Amgen Inc; Joseph G Ibrahim, University of North Carolina Chapel Hill
8:35 AM
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Bayesian Estimation of Analyte Concentrations using Sensor Responses and Design Optimization of a Sensor System
David Han, University of Texas At San Antonio
8:50 AM
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Formulation of Data Monitoring Committee Recommendations for Adaptive Design Clinical Trials
Navneet Hakhu, Axio Research
8:50 AM
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A Bayesian Logistic Model with Covariate to Identify Optimal Dose for Heterogeneous Population in Phase I Oncology Trial
Xin Wei, Celgene Corporation; Michael Branson, celgene corporation
8:50 AM
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Sources of Safety Data and Statistical Strategies for Design and Analysis: Real World Insights
Olga Marchenko, Bayer
8:55 AM
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Optimal Tradeoffs Between Generalized Design Goals in Multivariate Matching
Samuel David Pimentel, University of California, Berkeley; Rachel R. Kelz, University of Pennsylvania
9:00 AM
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Statistically Supporting Health Policy Decision-Making
Frank Yoon, IBM Watson Health
9:00 AM
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Efficient Two-Stage Designs and Proper Inference for Animal Studies
Chunyan Cai, UT Health Science Center at Houston; Jin Piao, University of Southern California; Jing Ning, The University of Texas M.D. Anderson Cancer Center; Xuelin Huang, University of Texas MD Anderson Cancer Center
9:05 AM
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Improving the Design of Pragmatic Clinical Trials Using Data Collected from Electronic Medical Records
Susan Shortreed, Kaiser Permanente Washington Health Research Institute; Carlyn M Rutter, RAND Corporation; Andrea J. Cook, Kaiser Permanente Washington Health Research Institute; Greg Simon, Kaiser Permenete Washington Health Research Insitute
9:15 AM
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A Novel Framework for Bayesian Response-Adaptive Randomization
Jian Zhu, Takeda; Ina Jazic, Harvard University; Yi Liu, Takeda Pharmaceuticals
9:50 AM
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Designing A/B Tests in a Collaboration Network
Sangho Yoon, Google
9:50 AM
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Assessing Health Care Interventions via an Interrupted Time Series Model: Study Power and Design Considerations
Maricela Cruz, University of California, Irvine; Miriam Bender, University of California, Irvine; Daniel L. Gillen, University of California, Irvine; Hernando Ombao, King Abdullah University of Science and Technology
9:55 AM
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A DCp Criterion for Nonparametric First Derivative Estimation
Sisheng Liu, Fred Hutchinson Cancer Research Center; Richard Charnigo, University of Kentucky; Cidambi Srinivasan, University of Kentucky
9:55 AM
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Two-Phase Outcome-Dependent Sampling Design with Interval-Censored Failure Time Data
Qingning Zhou, University of North Carolina at Charlotte; Jianwen Cai, University of North Carolina; Haibo Zhou, University of North Carolina
9:55 AM
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Closed-Form Solutions for Group Sequential Design in Survival Trials with Non-Proportional Hazards
Jianliang Zhang, Medimmune, LLC; Erik Pulkstenis, AbbVie
10:05 AM
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Helping All Students Properly Design and Analyze Experiments
Jennifer Broatch, Arizona State University
10:05 AM
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A Bayesian Phase I/II Trial Design for Immunotherapy
Suyu Liu, MD Anderson Cancer Center; Beibei Guo, Louisiana State University; Ying Yuan, University of Texas M.D. Anderson Cancer Center
10:35 AM
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Effective Data Competition Hosting: Strategic Design and Analysis to Maximize Learning
Christine M Anderson-Cook, Los Alamos National Laboratory; Kary Myers, Los Alamos National Laboratory
10:35 AM
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A Construction of Cost-Efficient Designs with Guaranteed Repeated Measurements on Interaction Effects
Frederick Kin Hing Phoa, Academia Sinica
10:35 AM
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Using Modified Competitive Swarm Optimizer to Find D-Optimal Designs for Complicated Logistic Models
Zizhao Zhang, UCLA; Weng Kee Wong, UCLA
10:45 AM
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Design and Analysis Considerations for Studies Involving Pooled Biomarker Data
Abigail Sloan, Harvard T.H. Chan School of Public Health; Molin Wang, Harvard T.H. Chan School of Public Health; Mitchell H. Gail, Division of Cancer Epidemiology and Genetics, NCI, NIH
10:50 AM
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Inference on Treatment Effect Modification by Marker Response in a Baseline Surrogate Measure Three-Phase Sampling Design
Michal Juraska, Fred Hutchinson Cancer Research Center; Ying Huang, Fred Hutchinson Cancer Research Center; Peter Gilbert, Fred Hutchinson Cancer Research Center
10:50 AM
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Uncertainty in the Design Stage of Two-Stage Bayesian Propensity Score Analysis
Shirley Liao
10:50 AM
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Efficient Design and Analysis of Cluster Randomized Trials
Hengshi Yu, University of Michigan, Ann Arbor; Fan Li, Duke Univeristy; John A. Gallis, Duke University; Elizabeth L. Turner, Duke Global Health Institutes
11:00 AM
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Bayesian Design of Experiments with Multiple Priors for Kaggle Competition Design
Kevin Randal Quinlan, The Pennsylvania State University; Christine M Anderson-Cook, Los Alamos National Laboratory
11:05 AM
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Embedding Observational Studies into Hypothetical Fractional-Factorial Experiments
Nicole Pashley, Harvard University; Marie-Abele Bind, Harvard University
11:35 AM
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Epidemiological Modeling to Guide Efficacy Study Design Evaluating Vaccines to Prevent Emerging Diseases
An Vandebosch, Janssen; Joris Menten, Janssen ; Guillermo Herrera-Taracena, Janssen
11:35 AM
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Leveraging Multiple Study Designs and Statistical Methods to Evaluate Comparative Effectiveness of Asthma Medications
Tebeb Gebretsadik, Vanderbilt University Medical Center; Pingsheng Wu, Vanderbilt University; Rees L Lee, U. S. Navy; Amber M Evans, Health ResearchTX LLC; Tan Ding, Vanderbilt University Medical Center; Nicholas M Sicignano, Health Research Tx ; Ann Wu, Harvard Medical School; Carlos Iribarren, Kaiser Permanente Division of Research; Butler Melissa, Kaiser Permanente; Chang Yu, Vanderbilt University Medical Center; William Dupont, Vanderbilt University Medical Center; Christina Fox, Health ResearchTx; Tina V Hartert, Vanderbilt University Medical Center
11:45 AM
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Practical Considerations on the Challenges to the Design and Analysis of Immuno-Oncology Trials
Yabing Mai, AbbVie, Inc; Yue Shentu, Merck and Co Inc
11:50 AM
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Using Concomitant and Nested Simulation for Tail Risk Measure Estimation
Mingbin Feng, University of Waterloo
11:55 AM
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A Comparison of Modeling Approaches for Stepped-Wedge Cluster Randomized Trials That Include Multilevel Clustering, Confounding by Time, and Effect Modification
Lance Ford, University of Oklahoma Health Sciences Center; Julie A Stoner, University of Oklahoma Health Sciences Center; Daniel Zhao, OU Health Sciences Center; Tabitha Garwe, University of Oklahoma Health Sciences Center; Ann Chou, University of Oklahoma Health Sciences Center; Daniel Duffy, University of Oklahoma-Tulsa
11:55 AM
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Universal Convergence of Kriging
C. F. Jeff Wu, Georgia Institute of Technology; Rui Tuo, Chinese Academy of Sciences; Wenjia Wang, Georgia Institute of Technology
2:05 PM
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Statistical Issues in the Design and Analysis of Sequencing Studies
Danyu Lin, University of North Carolina
2:05 PM
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Power Approximations for Reliability Test Designs
Rebecca Dickinson
2:05 PM
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An Application of 2-In-1 Adaptive Phase 2/3 Design for Expedited Oncology Drug Development
Xinqun (Maggie) Chen, Merck & Co., Inc.; Linda Sun, Merck & Co., Inc.; Cong Chen, Merck & Co.
2:05 PM
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A Location-Adjusted Approach to the Covariate-Adjusted Response-Adaptive Allocation Design in Multi-Center Trials
Brian S Di Pace, Virginia Commonwealth University; Roy T Sabo, Virginia Commonwealth University; David C. Wheeler, Virginia Commonwealth University
2:10 PM
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Design-Based Alternative Calibration Weighting Under Nonresponse in Survey Sampling
Per Andersson, Stockholm University
2:20 PM
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Considering Delayed Treatment Effect in Trial Designs with Survival Endpoints
Kaushal Mishra, Novartis Oncology Pharmaceuticals; Kalyanee Viraswami Appanna, Novartis Pharmaceuticals
2:20 PM
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A Generalized Design for a Confirmatory Basket Trial
Robert Beckman, Georgetown University; Xiaoyun (Nicole) Li, Merck
2:25 PM
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Planning a Missile Test Using Bayesian Sequential Design of Experiments
Keyla Pagan-Rivera
2:25 PM
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Screening for Important Factors in Computer Experiments
David Steinberg, Tel Aviv University; Natalie Abel, Tel Aviv University
2:30 PM
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Multiple Imputation for Adaptive Survey Design
Trivellore Raghunathan, University of Michigan
2:30 PM
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Phase I Designs That Allow for Uncertainty in the Attribution of Adverse Events
Alexia Iasonos, Memorial Sloan Kettering Cancer Center; John O'Quigley, Universit'e Pierre et Marie Curie,
2:35 PM
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Application of Bayesian Analyzes to Doubly-Randomized Delayed-Start, Matched Control Designs to Demonstrate Disease Modification
Ibrahim Turkoz, Janssen Research and Development, LLC; Marcus Sobel, Temple Universisity; Larry Alphs, Janssen Scientific Affairs, LLC
2:35 PM
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Comparing MandS Output to Live Test Data: a Missile System Case Study
Kelly M Avery, Institute for Defense Analyses
2:45 PM
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GBM AGILE: a Phase II/III Platform Design with Signature Identification
Todd Graves, Berry Consultants LLC; Donald A Berry, Berry Consultants and M.D. Anderson Cancer Center; Jason Connor, ConfluenceStat LLC
2:45 PM
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Capture-Recapture Methods for Data on the Activation of Applications on Mobile Phones
Mamadou YAUCK, Universite Laval; Louis-Paul Rivest, Université Laval; Greg Rothman, NinthDecimal
2:50 PM
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A Strategy for the Design and Analysis of Bridging Studies
Eric Holmgren, Beigene
2:50 PM
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Design of Experiments for the Calibration of Computational Models
David Woods, University of Southampton; Yiolanda Englezou, University of Southampton; Timothy Waite, University of Manchester
2:55 PM
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Improvements to the Escalation with Overdose Control Design and a Comparison with the Restricted Continual Reassessment Method
Lingyun Ji, University of Southern California; Richard Sposto, University of Southern California; Juan Pablo Lewinger, University of Southern California; Mark Krailo, University of Southern California; David Conti, University of Southern California; Susan Groshen, University of Southern California; Shahab Asgharzadeh, University of Southern California
3:00 PM
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A Parametric Multiple Comparison Procedure for Clinical Trials with Planned Evaluation of Treatment Effect in Pre-Defined Subgroups and Interim Analyzes
Liang Fang, MyoKardia; Ron Yu, Gilead Sciences, Inc.; Zhishen Ye, Gilead Sciences; Neby Bekele, Gilead Sciences; Ming Lin, Gilead Sciences
3:05 PM
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Bayesian Isotonic Optimal Dose Design for Phase I/II Clinical Trials with Ordered Groups
Xiaoqiang Xue
3:05 PM
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On the Design of Sequence-Based Case-Control Studies with External Controls
Debashree Ray, Johns Hopkins University; Pranav Yajnik, University of Michigan; Michael Lee Boehnke, University of Michigan
3:20 PM
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Multiple Imputation Methods Addressing Planned Missingness in a Multi-Phase Survey
Irina Bondarenko, University of Michigan; Yun Li, University of Michigan; Paul Imbriano, University of Michigan
3:20 PM
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Tuesday, 07/31/2018
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A Bayesian-Frequentist Hybrid Sequential Design of a Single-Arm Study with Binary Outcome and Its Shiny App
Yansong Cheng, Alkermes
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Clinical Trial Design Comparison with Covariate-Adjusted and Response Adaptive Randomization
Wei Qiao, The University of Texas M.D. Anderson; Xuelin Huang, University of Texas MD Anderson Cancer Center; Jing Ning, The University of Texas M.D. Anderson Cancer Center
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Using the R Package: Recursive Partitioning for Modeling Survey Data (RPMS)
Daniell Toth, Bureau of Labor Statistics
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A Bayesian Adaptive Design in Cancer Phase I/II Trials with Drug Combinations Using Escalation with Overdose Control (EWOC) and Adaptive Randomization
Sungjin Kim, Cedars-Sinai Medical Center; José L. Jiménez, Politecnico di Torino; Mourad Tighiouart, Cedars-Sinai Medical Center
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Adaptive Design: Challenges in Practice
Michael Yang, NORC
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Sample Size in Adaptive Design with Treatment Selection
Zejiang Yang, Syneos Health
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Estimation and Inference for Cluster-Randomized Test-Negative Design Trials
Suzanne M. Dufault, University of California, Berkeley; Nicholas P. Jewell, University of California, Berkeley
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Sequential Parallel Comparison Design with Binary and Time-to-Event Outcomes
Rachel Silverman, Merck & Co.; Anastasia Ivanova, University of North Carolina, Chapel Hill; Jason P Fine, University of North Carolina at Chapel Hill
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The Modified Toxicity Probability Interval Design with Consideration of Late Onset Toxicities
Xiaohui Huang, Gilead Sciences; Guan Xing, Gilead Sciences
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A Novel Approach of Using Prior Elicitation Information to Direct Design of a Phase 2 POC Study
Geng Chen, GlaxoSmithKline; Jonathan Haddad, Glaxosmithkline
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Bayesian Methods in Real-World Evidence for Medicinal Product Development: Can Prior Distributions Provide a Platform for Creating Real-World Evidence?
John Loewy, Dataforethought
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Real Experiences with Experimental Design: Composite Pressure Vessel Life Predict
Anne Driscoll
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Seeking Optimal Oral Cancer Drug Combinations
Ricardo Palafox, CSU Fullerton; Jessica Jaynes , CSU Fullerton
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The Problem of Analytic Error in Secondary Analysis of Survey Data: What We Know, and What We Need to Do About It
Brady T. West, University of Michigan; Joe Sakshaug, University of Manchester
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Improvements to the Escalation with Overdose Control Design and a Comparison with the Restricted Continual Reassessment Method
Lingyun Ji, University of Southern California; Richard Sposto, University of Southern California; Juan Pablo Lewinger, University of Southern California; Mark Krailo, University of Southern California; David Conti, University of Southern California; Susan Groshen, University of Southern California; Shahab Asgharzadeh, University of Southern California
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Meta-Analysis of Survey-Based, Non-Experimental Individual Person Data with Heterogeneous Weighting Schemes
Anna-Carolina Haensch, GESIS Institute ; Bernd Weiss, GESIS - Leibniz-Institute for the Social Sciences
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STEPDOWN TESTING PROCEDURES for DOSE FINDING STUDY with ADAPTIVE DESIGN
Gang Jia, Merck & Co.
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Phase I Designs That Allow for Uncertainty in the Attribution of Adverse Events
Alexia Iasonos, Memorial Sloan Kettering Cancer Center; John O'Quigley, Universit'e Pierre et Marie Curie,
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Calibrated Bayesian Approach for Small Area Prevalence Estimation Using Survey Data with Replicate Weights
Trung Ha, University of Central Florida; Julia Soulakova, University of Central Florida
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Estimation and Inference of Domain Means Subject to Shape Constraints
Cristian Oliva, Colorado State University; Mary C. Meyer, Colorado State University; Jean D. Opsomer, Colorado State University
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Method for Evaluating Longitudinal Follow-Up Frequency: Application to Dementia Research
Leah Suttner, University of Pennsylvania; Sharon X Xie, University of Pennsylvania
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A Location-Adjusted Approach to the Covariate-Adjusted Response-Adaptive Allocation Design in Multi-Center Trials
Brian S Di Pace, Virginia Commonwealth University; Roy T Sabo, Virginia Commonwealth University; David C. Wheeler, Virginia Commonwealth University
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Design-Based Alternative Calibration Weighting Under Nonresponse in Survey Sampling
Per Andersson, Stockholm University
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Comparison of Group Testing Algorithms for Clustered Data
Ana Best, NIH NCI DCEG Biostatistics Branch; Paul S Albert, National Cancer Institute; Yaakov Malinovsky, University of Maryland Baltimore County Dept. of Mathematics and Statistics
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Some T-Tests for N-Of-1 Trials with Serial Correlation: Correction Factors for Trials with Few Observations
Reid D. Landes, University of Arkansas for Medical Sciences; Ji-Ling Tang, University of Arkansas for Medical Sciences; Mark S Mennemeier, University of Arkansas for Medical Sciences; J. Tyler Floyd, University of Central Arkansas; Anne Holbrook, McMaster University
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Some T-Tests for N-Of-1 Trials with Serial Correlation
Ji-Ling Tang, University of Arkansas for Medical Sciences; Reid D. Landes, University of Arkansas for Medical Sciences; Anne Holbrook, McMaster University; Mark S Mennemeier, University of Arkansas for Medical Sciences; J. Tyler Floyd, University of Central Arkansas
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Hybrid Cluster-Individual Randomization Allocation
Yi-Fan Chen, University of Illinois at Chicago; Jonathan Yabes, University of Pittsburgh
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Addressing Challenges in an International Study with Propensity Scores: a Case Study from Indonesia
Marissa Gargano, RTI International; Susan Edwards, RTI International
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Targeted Maximum Likelihood Estimation of Causal Effects Based on Observing a Single Time Series
Ivana Malenica; Mark van der Laan, UC Berkeley
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Design Considerations When Comparing Control, Treatment, and Treatment Plus in Randomized Trials
Abigail Shoben, Ohio State University
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Multiple Imputation Methods Addressing Planned Missingness in a Multi-Phase Survey
Irina Bondarenko, University of Michigan; Yun Li, University of Michigan; Paul Imbriano, University of Michigan
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Survey Design Tools and Considerations for Sustaining Large-Scale Monitoring Programs Aimed to Characterize Species Distributions
Katharine Banner, Montana State University; Kathryn Irvine, US Geological Survey; Thomas Rodhouse, National Park Service; Andrea Litt, Montana State University
8:35 AM
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Data-Driven Biomarker Evaluation in Adaptive Designs Using SIDES
Ilya Lipkovich, IQVIA; Alex Dmitrienko, Mediana Inc
8:35 AM
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Choice of Small Area Models Based on Sample Designs and Availability of Auxiliary Data in PIAAC Study
Jianzhu Li, Westat; Leyla Mohadjer, Westat; Wendy VanDeKerckhove, Westat; Lin Li, Westat; Tom Krenzke, Westat
8:35 AM
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Complexity of Implementing Sample Size Re-Estimation (SSR) in Oncology Trials
Alicia Zhang, Amgen; Yuqi Chen, Amgen; Chris Holland, Amgen
8:35 AM
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Addressing Challenges in an International Study with Propensity Scores: a Case Study from Indonesia
Marissa Gargano, RTI International; Susan Edwards, RTI International
8:45 AM
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Desirability Functions for Evaluating Clinical Trial Design Quality
Priscilla K Yen, UCLA; Weng Kee Wong, UCLA
8:50 AM
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STEPDOWN TESTING PROCEDURES for DOSE FINDING STUDY with ADAPTIVE DESIGN
Gang Jia, Merck & Co.
8:55 AM
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Experimental Design Issues in Choice Based Conjoint Applied to Patient Choice in Healthcare
Pallavi Chitturi, Temple University; Alexandra Carides, Temple University
9:05 AM
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Applications of the Parametric Approach to Estimation of Totals and Means for Complex Survey Data in the Presence of Full Response
Ismael Flores Cervantes, Westat
9:05 AM
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A Confirmatory Basket Trial Design for Multiple Tumor Types Based on Conditional Power
Huiling Li; Jianming Wang, Celgene Corporation; Yeongjin Gwon, University of Connecticut; Xiaolong Luo, Celgene Corporation
9:05 AM
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Functional Regression Models with Highly Irregular Designs
Justin Petrovich, Pennsylvania State University; Matthew Reimherr, Pennsylvania State University; Carrie Daymont, Penn State Hershey Medical Center
9:20 AM
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Design Considerations in Clinical Trials with Cure Rate Survival Data: a Case Study in Oncology
Grace Liu, Johnson & Johnson; Steven Sun, J&J; Tzu-min Yhe, janssen pharmaceuticals; Tianmeng Lyu, University of Minnesota; Rao Sudhakar, janssen pharmaceuticals; Bruce Xue, Johnson & Johnson China
9:20 AM
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Comparison of Group Testing Algorithms for Clustered Data
Ana Best, NIH NCI DCEG Biostatistics Branch; Paul S Albert, National Cancer Institute; Yaakov Malinovsky, University of Maryland Baltimore County Dept. of Mathematics and Statistics
9:30 AM
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Method for Evaluating Longitudinal Follow-Up Frequency: Application to Dementia Research
Leah Suttner, University of Pennsylvania; Sharon X Xie, University of Pennsylvania
9:35 AM
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A Case Study of a Bayesian Adaptive Dose-Finding Phase 2 Trial Design Using Go/No-Go Criteria and Adaptive Randomization
Ye Ting Du; James Bolognese, Cytel Inc
9:35 AM
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Basket Trials Design and Analysis in Non-Oncology Therapeutical Areas
Binbing Yu, MedImmune/AstraZeneca; Jingjing Chen, Takeda Pharmaceuticals; Dewei She, MedImmune/AstraZeneca; Jianliang Zhang, Medimmune, LLC
9:50 AM
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When to Use Commercial Data for Improved Efficiency
Edward English, NORC At the University of Chicago; Colm O'Muircheartaigh, NORC at the University of Chicago
9:50 AM
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Methods and Study Design for Integrating External Controls with Allele Frequencies
Megan Sorenson, University of Colorado Denver; Audrey Hendricks, University of Colorado - Denver
10:05 AM
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Using Baseline Data in Process Improvement
Stefan Steiner, University of Waterloo; Jock MacKay, University of Waterloo
10:35 AM
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Flexible Stochastic Growth Models and Their Experimental Design
Nikolaos Demiris, Athens University of Economics and Business; Konstantinos Kalogeropoulos, London School of Economics; Nikolas Kantas, Imperial College London
10:35 AM
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Fieldwork Monitoring for the European Social Survey: An Illustration with Belgium and the Czech Republic in Round 7
Caroline Vandenplas, KU Leuven; Geert Loosveldt, KU Leuven
10:35 AM
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Some T-Tests for N-Of-1 Trials with Serial Correlation
Ji-Ling Tang, University of Arkansas for Medical Sciences; Reid D. Landes, University of Arkansas for Medical Sciences; Anne Holbrook, McMaster University; Mark S Mennemeier, University of Arkansas for Medical Sciences; J. Tyler Floyd, University of Central Arkansas
10:35 AM
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Targeted Maximum Likelihood Estimation of Causal Effects Based on Observing a Single Time Series
Ivana Malenica; Mark van der Laan, UC Berkeley
10:35 AM
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Reversals in Early Phase Dose Finding Trials
Bethany Horton, University of Virginia; John O'Quigley, Universit'e Pierre et Marie Curie, ; Mark Conaway, University of Virginia
10:35 AM
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Estimation and Inference of Domain Means Subject to Shape Constraints
Cristian Oliva, Colorado State University; Mary C. Meyer, Colorado State University; Jean D. Opsomer, Colorado State University
10:40 AM
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Some T-Tests for N-Of-1 Trials with Serial Correlation: Correction Factors for Trials with Few Observations
Reid D. Landes, University of Arkansas for Medical Sciences; Ji-Ling Tang, University of Arkansas for Medical Sciences; Mark S Mennemeier, University of Arkansas for Medical Sciences; J. Tyler Floyd, University of Central Arkansas; Anne Holbrook, McMaster University
10:40 AM
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Hybrid Cluster-Individual Randomization Allocation
Yi-Fan Chen, University of Illinois at Chicago; Jonathan Yabes, University of Pittsburgh
10:45 AM
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A Note on Phase II Single-Arm Two-Stage Designs for Safety
Seongho Kim, Wayne State University; Weng Kee Wong, UCLA
10:50 AM
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Uncertainty in the Design Stage of Observational Studies
Matthew Cefalu, RAND Corporation; Corwin Zigler, Harvard T.H. Chan School of Public Health
10:55 AM
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Dynamic Question Ordering in Online Surveys
Kirstin Early, Oath; Jennifer Mankoff, University of Washington; Stephen E. Fienberg, Carnegie Mellon University
10:55 AM
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Meta-Analysis of Survey-Based, Non-Experimental Individual Person Data with Heterogeneous Weighting Schemes
Anna-Carolina Haensch, GESIS Institute ; Bernd Weiss, GESIS - Leibniz-Institute for the Social Sciences
11:05 AM
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Calibrated Bayesian Approach for Small Area Prevalence Estimation Using Survey Data with Replicate Weights
Trung Ha, University of Central Florida; Julia Soulakova, University of Central Florida
11:20 AM
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The Welch's T-Test with Covariates
Cong Cao, The University of Texas at Dallas; Markus Pauly, Ulm University; Frank Konietschke, The University of Texas at Dallas
11:20 AM
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Covering Arrays: An Efficient Tool for Validating Complex Engineered Systems
Ryan Lekivetz, SAS Institute, Inc.; Joseph Morgan, SAS Institute, Inc.
11:35 AM
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The Problem of Analytic Error in Secondary Analysis of Survey Data: What We Know, and What We Need to Do About It
Brady T. West, University of Michigan; Joe Sakshaug, University of Manchester
11:40 AM
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Biomarker-Defined Subgroup Selection Adaptive Design for Phase III Confirmatory Trial
Rui Tang, Shire; Xiaoye Ma, University of Minnesota; Hui Yang, Amgen Inc.
11:50 AM
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AAA: Triple-Adaptive Bayesian Designs for the Identification of Optimal Dose Combinations in Dual-Agent Dose-Finding Trials
Jiaying Lyu, University of Chicago; Fudan University; Yuan Ji, NorthShore Univ. HealthSystem / The University of Chicago
11:55 AM
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Design Considerations When Comparing Control, Treatment, and Treatment Plus in Randomized Trials
Abigail Shoben, Ohio State University
12:05 PM
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Optimal Regression Designs Under the Second-Order Least Squares Estimator
Julie Zhou, University of Victoria; Chi-Kuang Yeh, University of Victoria
2:05 PM
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If it Is in the Electronic Health Record, Then it Must Be True
Jareen Meinzen-Derr, Cincinnati Children's Hospital Med Center
2:05 PM
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Calling All Stakeholders: Developing a Demographic Statistical Redesign Research Agenda
Richard Levy, U.S. Census Bureau; Jimmie B Scott, U.S. Census Bureau
2:05 PM
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An Overview of 2020 Census Design
Robin A Pennington, US Census Bureau; Gina Walejko, U.S. Census Bureau
2:20 PM
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Estimating the Receiver Operating Characteristic Curve from Clustered Data and Case-Control Studies
Yalda Zarnegarnia, University of Miami; Shari Messinger, University of Miami
2:20 PM
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Analysis of Competing Risk Data in Generalized Case-Cohort Design
Yayun Xu, Medical College of Wisconsin; Soyoung Kim, Medical College of Wisconsin
2:20 PM
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Development of a Processed Cheese Food Safety Model Using a Response Surface Design and Parametric Survival Modeling
Francis Rossi, PepsiCo
2:45 PM
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Evaluation of Therapeutic Effect in Clinical Study Using Companion Diagnostic Device for Patient Screening
Jeng Mah, Beckman Coulter
3:05 PM
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Application of State Health Status In the Design of the 2011-2014 National Health and Nutrition Examination Survey
Jay Clark, Westat; Leyla Mohadjer, Westat; Te-Ching Chen, National Center for Health Statistics
3:20 PM
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Improving the Quality and Value of Statistical Information: Fourteen Questions on Management
John L. Eltinge, United States Census Bureau
4:05 PM
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Wednesday, 08/01/2018
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Active Reference vs. Active Comparator: What Should We Include to Design Late-Phase Studies?
Suchitrita Rathmann, Eli Lilly & Co
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Successful Implementation of Bayesian Adaptive Designs in Medical Device Clinical Studies
Zengri Wang
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Practical Guidelines and User-Friendly Software for Bayesian Adaptive Designs
J. Jack Lee, Univ of Texas-M D Anderson Cancer Center
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Further Extensions of the Two-Stage Randomized Trial Design for Testing Treatment, Self-Selection and Treatment Preference Effects to Include Count Outcomes
Denise Esserman, Yale University; Yu Shi, Yale University
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Sample Size Estimation for Stratified Cluster Randomized Trials with Binary Outcomes
Lee Kennedy-Shaffer, Harvard University; Michael David Hughes, Harvard University
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Simulation-Based Bayesian Optimal Design for Ice Sheet Borehole Experiments
Xun Huan, Sandia National Labs/California; Andrew D. Davis, Massachusetts Institute of Technology
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Multi-Frame Sampling Design for WTCHR
Sukhminder Osahan, NYC DOHMH
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A Novel Blind Start Study Design to Investigate Vestronidase Alfa for Mucopolysaccharidosis VII, an Ultra-Rare Genetic Disease
Wenjie Song, Ultragenyx Pharmaceutical Inc; Chao-Yin Chen, Ultragenyx Pharmaceutical Inc; Christine Haller, Ultragenyx Pharmaceutical Inc; Emil Kakkis, Ultragenyx Pharmaceutical Inc
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Assessing MCP-Mod Relative to Pairwise Comparisons and Trend Tests in Dose-Ranging Design and Analysis
Anran Wang, Merck & Co Inc; Fang Liu, Merck & Co., Inc; Sammy Yuan, Merck; Man (Mandy) Jin, Merck & Co., Inc.; Meihua Wang, Merck & Co.; Akshita Chawla, Merck & Co Inc; Pranab Kumar Mitra, Merck & Co Inc; Robin Mogg, Merck Research Laboratories
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Bayesian Adaptive Design of Phase 2 Dose-Finding Study
Tanya Granston, CTI BioPharma Corp.; Huafeng Zhou, CTI BioPharma Corp.; Lixia Wang, CTI BioPharma Corp.
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A Two-Stage, Phase II Clinical Trial Design with Nested Criteria for Early Stopping and Efficacy: Expected Trial Duration and Tools for Planning
Michelle DeVeaux, Regeneron Pharmaceuticals; Michael John Kane, Yale University; Daniel Zelterman, Yale University
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Bayesian Analysis of Unrelated Question Design for Correlated Sensitive Questions from Small Areas
Yuan Yu
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Small Data and N-of-1 Trials: Developing Personalized Biostatistics for Personalized Medicine and Individualized Health Care Delivery
Christopher Schmid, Brown University; Deborah Estrin , Cornell Tech; Ying Kuen Ken Cheung, Columbia University; Mark Drangsholt, University of Washington; Richard L. Kravitz, University of California Davis; Xiao-Li Meng, Harvard University
8:35 AM
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Subgroup Selection in Adaptive Signature Designs of Confirmatory Clinical Trials
Zhiwei Zhang, University of California at Riverside
8:35 AM
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Simulation-Based Bayesian Optimal Design for Ice Sheet Borehole Experiments
Xun Huan, Sandia National Labs/California; Andrew D. Davis, Massachusetts Institute of Technology
8:35 AM
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Multi-Frame Sampling Design for WTCHR
Sukhminder Osahan, NYC DOHMH
8:40 AM
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A Novel Blind Start Study Design to Investigate Vestronidase Alfa for Mucopolysaccharidosis VII, an Ultra-Rare Genetic Disease
Wenjie Song, Ultragenyx Pharmaceutical Inc; Chao-Yin Chen, Ultragenyx Pharmaceutical Inc; Christine Haller, Ultragenyx Pharmaceutical Inc; Emil Kakkis, Ultragenyx Pharmaceutical Inc
8:40 AM
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A Powerful Approach to the Study of Moderate Effect Modification in Observational Studies
Kwonsang Lee, Harvard University; Dylan Small, University of Pennsylvania; Paul Rosenbaum, University of Pennsylvania
8:50 AM
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A Case Study of Adaptive Seamless Design with Subpopulation Selection in Oncology
Rui Qin, Janssen Pharmaceutical R&D
8:55 AM
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Multiply Imputing Missing Values Arising by Design in Transplant Survival Data
Robin Mitra, University of Lancaster
9:05 AM
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A Probability Based Method for Selecting the Optimal Personalized Treatment from Multiple Treatments
Karunarathna B Kulasekera, University of Louisville; Chathura Siriwardhana, University of Hawaii; Somnath Datta, University of Florida
9:15 AM
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Bayesian Blinded Sample Size Adjustment for Risk Differences
Andrew Hartley, PPD, Inc.
9:15 AM
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A Model-Based Approach for Simulating Adaptive Clinical Studies with Surrogate Endpoints Used for Interim Decision-Making
Xiaotian Chen, AbbVie; Alan Hartford, AbbVie Inc; Mei Li, AbbVie; Jun Zhao, AbbVie
9:20 AM
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Multiplicity for a Group Sequential Trial with Biomarker Subpopulations
Jing Zhao, Merck
9:20 AM
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Further Extensions of the Two-Stage Randomized Trial Design for Testing Treatment, Self-Selection and Treatment Preference Effects to Include Count Outcomes
Denise Esserman, Yale University; Yu Shi, Yale University
9:20 AM
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Deep Learning in Medical Imaging: Evaluation and Study Design
Robyn Ball, Stanford University; David Larson, Stanford University; Pranav Rajpurkar, Stanford University; Matthew Chen, Nines AI; Jeremy Irvin, Stanford University; Jaden Yang, Stanford University; Matthew P Lungren, Stanford University
9:20 AM
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Pseudo-Population Bootstrap Procedures for Multi-Stage Sampling Designs
Sixia Chen, University of Oklahoma; David Haziza, Université de Montréal
9:25 AM
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Sample Size Estimation for Stratified Cluster Randomized Trials with Binary Outcomes
Lee Kennedy-Shaffer, Harvard University; Michael David Hughes, Harvard University
9:30 AM
|
Bayesian Adaptive Design of Phase 2 Dose-Finding Study
Tanya Granston, CTI BioPharma Corp.; Huafeng Zhou, CTI BioPharma Corp.; Lixia Wang, CTI BioPharma Corp.
9:45 AM
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Longitudinal Parametric Dose-Response Surface Model Assisted Early Phase Study Design
Yongming Qu, Eli Lilly and Company
9:50 AM
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A Two-Stage, Phase II Clinical Trial Design with Nested Criteria for Early Stopping and Efficacy: Expected Trial Duration and Tools for Planning
Michelle DeVeaux, Regeneron Pharmaceuticals; Michael John Kane, Yale University; Daniel Zelterman, Yale University
9:50 AM
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Selection of the Optimal Personalized Treatment from Multiple Treatments with Multivariate Outcome Measures
Somnath Datta, University of Florida; Chathura Siriwardhana, University of Hawaii; Karunarathna B Kulasekera, University of Louisville
9:55 AM
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Assessing MCP-Mod Relative to Pairwise Comparisons and Trend Tests in Dose-Ranging Design and Analysis
Anran Wang, Merck & Co Inc; Fang Liu, Merck & Co., Inc; Sammy Yuan, Merck; Man (Mandy) Jin, Merck & Co., Inc.; Meihua Wang, Merck & Co.; Akshita Chawla, Merck & Co Inc; Pranab Kumar Mitra, Merck & Co Inc; Robin Mogg, Merck Research Laboratories
9:55 AM
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Adaptive Multi-Combination Platform Trials in Oncology; Considerations for Study Designs
Stuart Bailey, Novartis Institutes for Biomed Research; Jennifer Gauvin, Novartis
9:55 AM
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Bayesian Analysis of Unrelated Question Design for Correlated Sensitive Questions from Small Areas
Yuan Yu
10:05 AM
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Evaluating the Statistical Properties of Bayesian Basket Trial Designs
Kristen May Cunanan, Memorial Sloan Kettering Cancer Center; Alexia Iasonos, Memorial Sloan Kettering Cancer Center; Ronglai Shen, Memorial Sloan-Kettering Cancer Center; Colin B Begg, Memorial Sloan Kettering Cancer Center; Mithat Gonen, Memorial Sloan Kettering Cancer Center
10:35 AM
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Novel Model-Assisted Designs for Phase I Drug Combination Trials
Ruitao Lin, MD Anderson Cancer Center
10:35 AM
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What Constitutes Scientific Evidence - Controversies in Rare Disease Trial Designs and Personalized Medicine
Mark Chang, Veristat
10:35 AM
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Estimating Probability of Simultaneous Success with Multiple Endpoints Using Truncated Multi-Variate Correlated Normal Distribution
Tianshuang Wu, AbbVie; Yihua Gu, AbbVie; Ziqian Geng, AbbVie; Saurabh Mukhopadhyay, AbbVie
10:50 AM
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Bayesian Uncertainty Directed Trial Designs
Lorenzo Trippa, Harvard
11:05 AM
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Setting Up the Organization for Analytics
Michiko I Wolcott, Msight Analytics
11:15 AM
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On Randomized Controlled Trials with Integrated Real World Evidence for Drug Development in Rare Diseases
Qing Liu, Amicus Therapeutics, Inc
11:15 AM
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On Statistical Inference in Factorial Multi-Reader Studies Using Bootstrap
Andriy Bandos, University of Pittsburgh
11:20 AM
|
Group Sequential Tests of Treatment Effect on Survival and Cumulative Incidence at a Fixed Time Point
Michael Martens, The Emmes Corporation; Brent Logan, Medical College of Wisconsin
11:35 AM
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Adaptive Dose Finding in Oncology Phase I-II Studies with Consideration of Tolerability and Efficacy
Rachael Liu, Takeda Pharmaceuticals ; Ling Wang, Takeda; David Sinclair, Google; Jianchang Lin, Takeda Pharmaceuticals
11:35 AM
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AAA: Triple-Adaptive Bayesian Designs for the Identification of Optimal Dose Combinations in Dual-Agent Dose-Finding Trials
Yuan Ji, NorthShore Univ. HealthSystem / The University of Chicago; Jiaying Lyu, Fudan Universtiy
11:35 AM
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Efficient Construction of Bayes Optimal Designs for Stochastic Process Models
Richard Boys, Newcastle University
2:05 PM
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Utilizing the Block Diagonal Covariance Structure of Nonregular Two-Level Designs
Robert Mee, University of Tennessee; David J Edwards, Virginia Commonwealth University
2:05 PM
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T-Optimal Design for Multivariate Polynomial Regression Using Semidefinite Programming
Yuguang Yue, The University of Texas At Austin; Weng Kee Wong, UCLA; Lieven Vandenberghe, University of California, Los Angeles
2:05 PM
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Individual Clear Effects for Fractional Factorial Designs
William Li, Shanghai Advanced Institute of Finance
2:20 PM
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Considerations in Designing the 2020 Post-Enumeration Survey Sample
Laura A. Davis, US Census Bureau; T. Trang Nguyen, US Census Bureau; Courtney Hill, U.S. Census Bureau
2:25 PM
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Bayesian Design for Intractable Models
Antony Overstall, University of Southampton
2:25 PM
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Dependencies in Binary Regression Data Generated by Informed Sequential Dose Allocation
Nancy Flournoy, University of Missouri; Assaf Oron, Instutue for Disease Modeling
2:25 PM
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Integrating Auxiliary Data in Optimal Spatial Design for Species Distribution Mapping
Jonathan Stallings, North Carolina State University; Brian Reich, North Carolina State University; Krishna Pacifici, North Carolina State University
2:30 PM
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Developments of the Synthetic Likelihood Approach for Bayesian Design for Models with Intractable Likelihoods
James McGree
2:45 PM
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Frequentist Decision-Theoretic Optimal Design with Application to Nonlinear Models
Meshayil Alsolmi
2:50 PM
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Dimensional Analysis for Response Surface Methodology
Ching-Chi Yang, Penn State; Dennis Lin, Pennsylvania State University
2:50 PM
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Real-Time, Within-Person Randomization Using a Bandit Algorithm in a Clinical Trial
Susan Murphy, Harvard University
2:55 PM
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Optimal Bayesian Design for Models with Intractable Likelihoods via Machine Learning Methods
Christopher C Drovandi, Queensland University of Technology; Markus Hainy, QUT
3:05 PM
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Augmenting Definitive Screening Designs for Estimating Second-Order Models
Abigael Nachtsheim, Arizona State Univ
3:05 PM
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Model-Based Sampling Design for Multivariate Spatial Prediction on a Stream Network
Dale Zimmerman, American Statistical Association
3:20 PM
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Optimal Designs for Gamut Models
William Heavlin, Google, Inc.
3:20 PM
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Optimal Design for Queueing Systems: Maximal Information by Appropriate Measurement on Queues
Ben Parker, University of Southampton
3:25 PM
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Incorporating Design Weights and Historical Data into Model-Based Small-Area Estimation
Hui Xie, CDC; Lawrence Barker, CDC; Deborah Rolka, CDC
3:35 PM
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Hydraulic Fluids: a Case Study of a Split-Plot Experiment
Jennifer Kensler, Shell
3:35 PM
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Thursday, 08/02/2018
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Two Short or One Long: An Experiment Comparing Survey Length vs. Quantity of Surveys
Rebecca Powell, RTI International; Paul Biemer, RTI Internatinoal; Sarah Cook, RTI International; Kathleen Considine, RTI International; Carolyn Halpern, Carolina Population Center-UNC; Kathleen Harris, Carolina Population Center-UNC; Sarah Dean, Carolina Population Center-UNC
8:35 AM
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Utilization of Historical Data and Real World Evidence in Clinical Trial Development - Case Studies in Rare Disease and Oncology
Florence H Yong, Pfizer Inc.; Ray Li, Pfizer Inc.; Steven Y Hua, Celgene - Receptos; Jeffery Palmer, Pfizer Inc.; Roberto Bugarini, Pfizer Inc.
8:50 AM
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Multi-Response Based Personalized Treatment Selection for Multiple Treatments
Chathura Siriwardhana, University of Hawaii; Karunarathna B Kulasekera, University of Louisville
9:05 AM
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On Implementation of Iterative Algorithms of Model-Based Optimal Experimental Design on a Quantum Computer
Sergei Leonov, ICON Clinical Research
9:15 AM
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Finding and Combining Multiple Designed Data Sets for Estimating Causal Effects in Observational Studies
Zach Branson, Harvard University; Marie-Abele Bind, Harvard University
9:20 AM
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Extension to Signature Design
Xiting Yang, Food and Drug Administration
9:20 AM
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Selecting a Sample from a Changing Frame of Program Beneficiaries
Eric Grau, Mathematica Policy Research
9:35 AM
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Target Toxicity Design for Phase 1 Dose-Finding: a Safe and Reliable Method
Bob Zhong, Johnson and Johnson; Wenchuan Guo, University of California Riverside
9:50 AM
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Statistical Challenges and Opportunities in Drug Development for Rare Diseases
Guowen Sun, BioMarin; Keith Gregg, BioMarin; Peter Slasor, BioMarin; Chito Hernandez, BioMarin Pharmaceutical Inc.
9:50 AM
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Signal Aliasing in Gaussian Random Fields for Experiments with Qualitative Factors
Ming-Chung Chang; Shao-Wei Cheng, National Tsing Hua University; Ching-Shui Cheng, Academia Sinica
9:50 AM
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Data for Good: Designing for Impact
Jake Porway, DataKind
10:35 AM
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Information-Based Subdata Selection for LASSO Regression
Min Yang, University of Illinois at Chicago; Xin Wang, University of Illinois at Chicago
10:35 AM
|
A Bayesian Adaptive Phase 1/2 Design of Cisplatin and Cabazitaxel in Prostate Cancer with Visceral Metastasis
Mourad Tighiouart, Cedars-Sinai Medical Center
10:35 AM
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Adaptive Bayesian Interval-Based Oncology Dose Finding Design with Quasi-Continuous Toxicity Model
Dan Zhao, University of Illinois at Chicago; Jian Zhu, Takeda; Eric Westin, ImmunoGen; Ling Wang, Takeda
10:50 AM
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Simulation of Rainwater Harvesting and Demand-Side Water Conservation for Hospitals
Lawrence Fulton, Texas State University; Lana Ivanitskaya, Central Michigan University; Dmitry A. Erofeev, Central Michigan University
10:50 AM
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Evaluation of Treatment Effect: Beyond Traditional Subgroups
Yeh-Fong Chen, US FDA
10:55 AM
|
IMP: Interference Manipulating Permutations
Michael Baiocchi, Stanford University; Eric Jay Daza, Stanford University
11:00 AM
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Information-Based Subdata Selection
John Stufken, Arizona State University
11:00 AM
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Bayesian Predictive Probability for Interim Analysis
Dung-Tsa Chen, Moffitt Cancer Center
11:05 AM
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A Likelihood Ratio Test for Gene (G)-Environment (E) Interaction Based on the Trend Effect of a Genotype Under an Additive Risk Model Using the G-E Independence Assumption
Summer Han, Stanford University; Nilanjan Chatterjee, Johns Hopkins University
11:15 AM
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Designing a Group Major in Data Science
Deborah Nolan, University of California, Berkeley
11:20 AM
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Practical Considerations of Subgroups Quantification, Selection and Adaptive Enrichment in Confirmatory Trials
Jianchang Lin, Takeda Pharmaceuticals; Rachael Liu, Takeda Pharmaceuticals ; Veronica Bunn, Florida State University
11:20 AM
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First Reproducible Nationwide Survey on Substance Use in Brazil: Survey Design and Weighting
Pedro Luis do Nascimento Silva, IBGE-ENCE; Mauricio Teixeira Leite de Vasconcellos, IBGE-ENCE; Raquel B De Boni, FIOCRUZ; Francisco Inacio Pinkusfeld Monteiro Bastos, FIOCRUZ; Neilane Bertoni dos Reis, Instituto Nacional de Câncer; Carolina Fausto de Souza Coutinho, FIOCRUZ; Jurema Corrêa da Mota, FIOCRUZ; Lidiane da Silveira Gouvea Toledo, FIOCRUZ
11:20 AM
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Biomarker Guided Phase II Two-Stage Design for Targeted Therapy
Zheyu Wang, Johns Hopkins University; Fujun Wang, Medimmune; Chenguang Wang, Johns Hopkins University; Gary Rosner, Johns Hopkins University; Jianliang Zhang, Medimmune; Hao Wang, Johns Hopkins University; Li Shi, Medimmune
11:25 AM
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Causal Effects in Partially and Non-Randomized Two-Stage Designs with Interference
Avi Feller, UC Berkeley; Samuel David Pimentel, University of California, Berkeley; Panos Toulis, University of Chicago; Guillaume Basse, Harvard University; Luke J. Keele, University of Pennsylvania
11:25 AM
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Embracing Experimental Design Thinking for Large-Scale Statistical Analysis
Peter Chien, University of Wisconsin-Madison
11:25 AM
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Understand International Differences in Treatment Effect
Li Chen, Amgen
11:55 AM
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BOIN-ET: Bayesian Optimal Interval Design for Dose Finding Based on Both Efficacy and Toxicity Outcomes
Kentaro Takeda, Astellas Pharma Global Development, Inc.; Masataka Taguri, Yokohama City University; Satoshi Morita, Kyoto University
12:05 PM
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