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Keyword Search Criteria: NRI returned 17 record(s)
Sunday, 07/30/2017
An Optimized Adaptive Enrichment Design for Multi-Arm Trials
Michael Rosenblum, Johns Hopkins University; Aaron Fisher, Johns Hopkins University; Jon Steingrimsson, Johns Hopkins University; Joshua A Betz, Johns Hopkins University
2:25 PM

Sequential Patient Recruitment Monitoring
Dong-Yun Kim, NHLBI/NIH; Sung-Min Han, OSEHRA
2:45 PM

Monday, 07/31/2017
Enrichment by Response: Sequential Parallel Comparison Design
Anastasia Ivanova, UNC at Chapel Hill
10:35 AM

Estimators and Confidence Intervals for Adaptive Two-Stage Designs for Population Enrichment
Vladimir Dragalin, Janssen R&D; Ionut Bebu, The George Washington University
10:55 AM

An Adaptive Subgroup-Identification Enrichment Design
Yanxun Xu, Johns Hopkins University; Yili L Pritchett, MedImmune; Florica Constantine, Johns Hopkins University
11:15 AM

Assessment of Utility of Total Kidney Volume for Trial Enrichment
John Lawrence
11:35 AM

FUNctioNal ELastic-Net (FUNNEL) Pipeline for Gene Set Enrichment Analysis with Overlapping
Yun Zhang, University of Rochester; Juilee Thakar, University of Rochester; Xing Qiu, University of Rochester
2:05 PM

Adaptive Multi-Arm Multi-Stage Designs
Cyrus Mehta, Cytel Inc; Pranab Ghosh, Cytel Inc, Boston University
2:25 PM

ASID: A Bayesian Adaptive Subgroup-Identification Enrichment Design
Florica Constantine, Johns Hopkins University; Yanxun Xu, Johns Hopkins University; Yili L Pritchett, MedImmune; Zhilin Jin, Johns Hopkins University
2:50 PM

Confirmatory Group Sequential Adaptive Designs for Time-To-Event Endpoints Using a Short-Term Endpoint for Treatment Arm or Population Selection
Gernot Wassmer, Medical University of Vienna, Austria; Martin Posch, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University o; Franz Koenig, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University o; Silke Joergens, ICON Clinical Research Inc, Cologne Germany
3:05 PM

Tuesday, 08/01/2017
Measures of Predictive Model Performance and Event Rate: How Much They Vary and How to Make Them Comparable Across Studies
Olga Demler, Harvard Medical School; Nancy R. Cook, Harvard T. H. Chan School of Public Health
2:35 PM

Wednesday, 08/02/2017
Subgroup Identification of Early Preterm Birth (EPTB): Informing a Future Prospective Enrichment Clinical Trial Design
Chuanwu Zhang, University of Kansas Medical Center
9:05 AM

Stochastic Optimization of Adaptive Enrichment Designs for Two Subpopulations
Michael Rosenblum, Johns Hopkins University; Aaron Fisher, Harvard University-Department of Biostatistics; Joshua A Betz, Johns Hopkins University; Jon Steingrimsson, Johns Hopkins University
9:35 AM

Estimand in Evaluating Predictive or Selection Markers Using Enrichment Design in Clinical Trials
Jingjing Ye, FDA
9:55 AM

Thursday, 08/03/2017
Motivation and Design of the DIA Adaptive Design Scientific Working Group (DIA ADSWG) Survey for the Perception and Use of Adaptive Designs in Pharmaceutical Clinical Development
Alan Hartford, AbbVie
10:35 AM

Evaluating Imaging Inclusion Criteria for Stroke Clinical Trials: Appropriate Enrichment Versus Cherry Picking
Robyn L Ball, Stanford University; Bin Jiang, Stanford University; Manisha Desai, Stanford University; Max Wintermark, Stanford University
10:50 AM

A Large-Scale Genome-Wide Enrichment Analysis Identifies New Trait-Associated Genes, Pathways and Tissues Across 31 Human Phenotypes
Xiang Zhu, University of Chicago; Matthew Stephens, University of Chicago
12:05 PM

 
 
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