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Sessions Were Renumbered as of May 19.

Legend:
CC-W = McCormick Place Convention Center, West Building,   CC-N = McCormick Place Convention Center, North Building
H = Hilton Chicago,   UC= Conference Chicago at University Center
* = applied session       ! = JSM meeting theme

Keyword Search Criteria: Biomarker returned 66 record(s)
Sunday, 07/31/2016
Analysis of Longitudinal Multi-Sequence MRI in Multiple Sclerosis
Elizabeth M. Sweeney, Johns Hopkins Bloomberg School of Public Health ; Russell Shinohara, University of Pennsylvania; John Muschelli, The Johns Hopkins University; Daniel Reich , National Institute of Neurological Disorders and Stroke; Ciprian Crainiceanu, The Johns Hopkins University; Jonathan Gellar, Mathematica Policy Research; Philip Reiss, New York University/University of Haifa; Ani Eloyan, Brown University


Issues in Biomarker-Based Oncology Trial Design
Daniel Sargent, Mayo Clinic
2:05 PM

A Statistical Framework for Using External Information in Updating Prediction Models with New Biomarker Measures
Wenting Cheng, University of Michigan; Jeremy M. G. Taylor, University of Michigan; Bhramar Mukherjee, University of Michigan
2:20 PM

Accuracy Measures for Predictive Biomarkers
Richard Macey Simon, National Cancer Institute
2:25 PM

Developing Combinations of Prognostic and Diagnostic Biomarkers in Multicenter Studies
Allison Meisner, University of Washington; Kathleen F. Kerr, University of Washington
2:35 PM

Adjusting for Enrichment Effects When Estimating Oncology Biomarker Clinical Utility
Jared Lunceford, Merck Research Laboratories
2:45 PM

Bias in Lifetime Data Analysis for Validation of Biomarkers
Tinghui Yu, FDA/CDRH; Yabing Mai, Merck Research Laboratories
3:05 PM

Alzheimer's Disease Severity, Objectively Determined and Measured
Alden Gross, Johns Hopkins Bloomberg School of Public Health; Jeannie M. Leoutsakos, The Johns Hopkins University; Marilyn Albert, The Johns Hopkins University; Dan M. Mungas, University of California at Davis; Richard Norman Jones, Brown University
4:55 PM

Monday, 08/01/2016
Meta-Analysis of Predictive Values of Biomarkers
Mun Sang Yue, Brown University; Constantine Gatsonis, Brown University


Genomic Determination Index
Cheng Cheng, St. Jude Children's Research Hospital; Robert J. Autry, St. Jude Children's Research Hospital; Wenjian Yang, St. Jude Children's Research Hospital; Steven Paugh, St. Jude Children's Research Hospital; William E. Evans, St. Jude Children's Research Hospital
8:50 AM

A Flexible Joint Longitudinal-Survival Model for Quantifying the Association Between Serum Biomarkers and Mortality
Daniel Gillen, University of California at Irvine; Sepehr Arkhavan, University of California at Irvine; Babak Shahbaba, University of California at Irvine
9:25 AM

Quantifying Treatment Benefit in Molecular Subgroups to Assess a Predictive Biomarker
Jaya M. Satagopan, Memorial Sloan Kettering Cancer Center; Alexia Iasonos, Memorial Sloan Kettering Cancer Center
10:35 AM

Machine-Learning Tools for Finding Biomarkers in Precision Medicine
Jonathan Hibbard, The University of North Carolina at Chapel Hill; Michael R. Kosorok, The University of North Carolina at Chapel Hill
11:00 AM

Optimal Sampling Designs of Two-Compartment Nonlinear Regression Models
Noa Molshatzki, University of Southern California; Sandrah P. Eckel, University of Southern California
11:05 AM

Efficient Design and Analysis to Evaluate the Incremental Values of Novel Prognostic Markers
Yingye Zheng, Fred Hutchinson Cancer Research Center; Tianxi Cai, Harvard
11:25 AM

Personalized Screening Intervals for Biomarkers Using Joint Models for Longitudinal and Survival Data
Dimitris Rizopoulos, Erasmus University Medical Center
2:05 PM

Functional Data Analysis Approach for Using Longitudinal Biomarker to Predict Disease Progression
Xuelin Huang, MD Anderson Cancer Center; Fangrong Yan, China Pharmaceutical University/MD Anderson Cancer Center; Xiao Lin, China Pharmaceutical University
2:30 PM

Enrichment Design with Patient Augmentation for Time-to-Event Data
Yijie Zhou, AbbVie; Bo Yang, Vertex Pharmaceuticals; Lanju Zhang, AbbVie; Lu Cui, AbbVie
2:50 PM

Analysis of High-Throughput Drug Screening Data of Cancer Cell Lines
Hongmei Liu; J. Sunil Rao, University of Miami
2:50 PM

Dynamic Prediction by Landmarking in Clinical Survival Analysis
Hans C. van Houwelingen, Leiden University Medical Center
2:55 PM

Characterizing the Prognostic Potential of Dynamic Markers: Connections to Information Theory
Patrick Heagerty, University of Washington; Jason Chao-Kang Liang, Fred Hutchinson Cancer Research Center
3:20 PM

Tuesday, 08/02/2016
A Random Forest of Modified Interaction Trees for Treatment Decision Rules
Zhen Zeng, Merck; Zheng Wei, Sanofi US; Yuefeng Lu, Sanofi US


Adjusting for Noncompliance in Randomized Clinical Trials When Noncompliance Must Be Estimated from a Biomarker
Jeffrey Boatman; David Vock, University of Minnesota School of Public Health; Joseph S. Koopmeiners, University of Minnesota


Statistics and Biology: Stories with Heart
Elizabeth Ribble, Metropolitan State University of Denver


Biomarker Detection and Categorization in RNA-Seq Meta-Analysis Using Bayesian Hierarchical Model
Tianzhou Ma, University of Pittsburgh; Faming Liang, University of Florida; George Tseng, University of Pittsburgh
8:35 AM

Efficient Method to Optimally Identify Important Biomarkers for Disease Outcomes with High-Dimensional Data
Xiang Li, Columbia University; Shanghong Xie, Columbia University; Donglin Zeng, The University of North Carolina at Chapel Hill; Yuanjia Wang, Columbia University
8:35 AM

Logical Inference of Efficacy in Subgroups and Their Combinations
Jason C. Hsu, Eli Lilly and Company/The Ohio State University
9:05 AM

Multiplicity Adjustment Strategy for Oncology Biomarker Trials
Shu-Chih Su, Merck; Jing Zhao, Merck
9:50 AM

Adjusting for Noncompliance in Randomized Clinical Trials When Noncompliance Must Be Estimated from a Biomarker
Jeffrey Boatman; David Vock, University of Minnesota School of Public Health; Joseph S. Koopmeiners, University of Minnesota
10:05 AM

Biomarker Analyses in Phase II Dose-Ranging Study
Xiwen Ma, Sanofi US; Yuefeng Lu, Sanofi US; Zheng Wei, Sanofi US
10:35 AM

A Random Forest of Modified Interaction Trees for Treatment Decision Rules
Zhen Zeng, Merck; Zheng Wei, Sanofi US; Yuefeng Lu, Sanofi US
10:35 AM

Evaluation of Magnetic Resonance Imaging (MRI) Parameters as Biomarkers in Alzheimer's Disease
Leacky Muchene, Hasselt University; Ziv Shkedy, Hasselt University; Luc Kamau Bijnens, Janssen; Nikolay Manyakov, Janssen; Tom Van De Kasteel, Janssen; Tom Jacobs, Janssen; Marleen Kamau Verhoye, Antwerp University; Jelle Praet, Antwerp University; Annemie Van der Linden, Antwerp University; Astrid Bottelbergs, Janssen; Mark Schmidt, Janssen; Darrel Pemberton, Janssen
10:50 AM

Link-Free Identification of Simple Index Variables for the Prediction of Differential Treatment Response
Hongjie Zhu, Sanofi
11:05 AM

Adapting Heterogeneous Tissue Expression Analysis Method to RNA-Seq Data
Megan Stefanski, University of Missouri - Kansas City; David Spade, University of Missouri - Kansas City
11:35 AM

Bias Correction for Biomarker Threshold Studies
Li Liu, Sanofi; Glen Laird, Sanofi
11:50 AM

Statistics and Biology: Stories with Heart
Elizabeth Ribble, Metropolitan State University of Denver
11:50 AM

Dynamic Prediction of Alzheimer's Disease Risk Based on Longitudinal Biomarkers and Functional Data
Sheng Luo, The University of Texas at Houston; Kan Li, The University of Texas at Houston
11:55 AM

Module-Based Reconstruction of Gene Regulatory Network into Predictive Modeling for High-Dimensional Genomic Data
Rui Zhong, AbbVie; Xin Huang, AbbVie; Viswanath Devanarayan, AbbVie
2:35 PM

Multiple Imputation Methods to Enhance the NHANES-CMS Medicaid Linked Data - Demonstrated by Examining Cotinine as a Biomarker for Second-Hand Smoke Among Children Ages 3--17
Jennifer Rammon, CDC
2:50 PM

Wednesday, 08/03/2016
The Key Role of Statistics in Neuroimaging: Challenges and Opportunities
DuBois Bowman, Columbia University


Simultaneous Confidence Intervals for Assessing SNP Effects on Treatment Efficacy
Yushi Liu; Jason C. Hsu, Eli Lilly and Company/The Ohio State University


Adaptive Estimation of Personalized Maximum Tolerated Doses in Cancer Phase I Clinical Trials According to All Toxicities and Individual Characteristics
Zhengjia Chen, Emory University; Zheng Li, Penn State University; Ying Yuan, MD Anderson Cancer Center; Michael Kutner, Emory University; Taofeek Owonikoko, Emory University; Walter J. Curran, Emory University; Jeanne Kowalski, Emory University


Adaptive Estimation of Personalized Maximum Tolerated Doses in Cancer Phase I Clinical Trials According to All Toxicities and Individual Characteristics
Zhengjia Chen, Emory University; Zheng Li, Penn State University; Ying Yuan, MD Anderson Cancer Center; Michael Kutner, Emory University; Taofeek Owonikoko, Emory University; Walter J. Curran, Emory University; Jeanne Kowalski, Emory University
8:45 AM

Subgroup Analysis in Regulatory Decision Making
Lilly Yue, FDA/CDRH/OSB
9:15 AM

Historical Functional Cox Regression, with an Application to Prediction of Multiple Sclerosis Lesions
Philip Reiss, New York University; Elizabeth M. Sweeney, Johns Hopkins Bloomberg School of Public Health ; Jonathan Gellar, Mathematica Policy Research
9:15 AM

Simultaneous Confidence Intervals for Assessing SNP Effects on Treatment Efficacy
Yushi Liu; Jason C. Hsu, Eli Lilly and Company/The Ohio State University
9:20 AM

Adaptive Enrichment Trials for Biomarker-Guided Treatments
Noah Simon, University of Washington; Richard Macey Simon, National Cancer Institute
9:25 AM

Multiple Imputation Method Based on Weighted Quantile Regression Models for Longitudinal Censored Biomarker Data with Missing Early Visits
MinJae Lee, The University of Texas Health Science Center at Houston ; Mohammad H. Rahbar, The University of Texas Health Science Center at Houston; John D. Reveille, The University of Texas Health Science Center at Houston ; Michael Weisman, Cedars-Sinai Medical Center; Michael M. Ward, National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lianne Gensler, University of California at San Francisco; Matthew Brown, University of Queensland Diamantina Institute
10:05 AM

Semiparametric Estimation and Inference for Partial AUC of Biomarkers Subject to Limit of Detection
Lixuan Yin, George Mason University; Guoqing Diao, George Mason University; Aiyi Liu, Eunice Kennedy Shriver National Institute of Child Health and Human Development
11:50 AM

Cross-Validated STEPP Analysis for Biomarker Subgroup Determination Problems
Gu Mi, Eli Lilly and Company; Tuan Stevon Nguyen, Eli Lilly and Company; Jonathan Denne, Eli Lilly and Company
3:20 PM

Thursday, 08/04/2016
Identifying Optimal Approaches to Early Termination in Two-Stage Biomarker Validation Studies
Alexander Kaizer, University of Minnesota; Joseph S. Koopmeiners, University of Minnesota
8:35 AM

Clustering Alzheimer's Patients into 'Syndrome Groups' Using Longitudinal Biomarker and Cognitive Trajectories
Teresa Filshtein, University of California at Davis; Laurel A. Beckett, University of California at Davis
8:50 AM

Comparison of Some Subgroup Identification Algorithms for Precision Medicine in Drug Development
Xin Huang; Yan Sun, AbbVie; Saptarshi Chatterjee, AbbVie; Viswanath Devanarayan, AbbVie
8:55 AM

Predicting Alzheimer's Disease with Mixture of Regression Modeling
Frank Appiah; David Fardo, University of Kentucky; Erin L. Abner, University of Kentucky; Glen Mays, University of Kentucky; Richard Charnigo, University of Kentucky
9:20 AM

Methods for Joint Clustering of Longitudinal HIV Biomarker Trajectories in the Presence of Missing and Censored Observations
Miranda Lynch, University of Connecticut Health Center; Marianna Baum, Florida International University; Vladimir Novitsky, Harvard T.H. Chan School of Public Health; Victor De Gruttola, Harvard
9:20 AM

Imaging Information Chaos: The Consequences of More Complete Imaging and Less Complete Understanding
David Raunig, ICON Medical Imaging
9:20 AM

Development of a Neuroimaging Biomarker for Lesion Recovery in Multiple Sclerosis
Elizabeth M. Sweeney, Johns Hopkins Bloomberg School of Public Health ; Michelle Ross , University of Pennsylvania; John Muschelli, The Johns Hopkins University; Benjamin Risk , Statistical and Applied Mathematical Sciences Institute; Daniel Reich , National Institute of Neurological Disorders and Stroke; Ani Eloyan , Brown University; Ciprian Crainiceanu, The Johns Hopkins University; Russell Shinohara, University of Pennsylvania
9:25 AM

Creating a Biomarker Signature for a Companion Diagnostic Using Bootstrapping and Aggregating Thresholds from Tree-Based Models
Raj Chandran
9:35 AM

Classification of Mixed Binary Outcomes Using Biomarker Information
Feng-Chang Lin, The University of North Carolina at Chapel Hill; Quefeng Li, The University of North Carolina at Chapel Hill
9:50 AM

Subgroup Identification in a Learn-and-Confirm Setting
Lei Shen, Eli Lilly and Company
9:55 AM

Optimal Decision Rule for Multiple Biomarkers Combined as Tree-Based Classifiers
Yuxin Zhu, The Johns Hopkins University; Mei-Cheng Wang, The Johns Hopkins University
10:05 AM

A Genomically Informed High-Dimensional Predictor for Microbial Community Metabolic Profiles
Himel Mallick, Harvard; Eric Franzosa, Harvard; Lauren Mclver, Harvard; Soumya Banerjee, Harvard; Alexandra Sirota-Madi, Broad Institute; Aleksandar Kostic, Broad Institute ; Clary B. Clish, Broad Institute; Hera Vlamakis, Broad Institute; Ramnik Xavier, Broad Institute; Curtis Huttenhower, Harvard
10:50 AM

Sample Size Methods for Validating Treatment Selection Cancer Biomarkers from Right-Censored Survival Data
Kevin Dobbin, University of Georgia; Lisa M. McShane, National Cancer Institute
11:05 AM

Statistical Methods for Computer Algorithm Comparisons in Quantitative Imaging Biomarkers
Huiman Barnhart, Duke University
11:15 AM

Construction of Genetic Biomarkers in Drug Discovery Experiments Using Joint Modeling Methods
Ziv Shkedy, Hasselt University
11:15 AM

Covariate-Adjusted ROC Analysis Using Covariate Balancing Propensity Score
Seungbong Han, Gachon University
11:35 AM

 
 
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