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Sunday, 08/04/2013
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An Integrated Approach to Identify Clinically Relevant Long Non-Coding RNAs (lncRNAs) in Cancer
Xiaole Shirley Liu, Dana-Farber and Harvard University
2:05 PM
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A Simulation Study to Evaluate Accuracy and Precision of Blinded Independent Central Reviews (BICR) on Progression-Free Survival in Cancer Clinical Trials
Fenghai Duan, Brown University; Richard Walovitch, WorldCare Clinical, LLC; Vincent Girardi, WorldCare Clinical, LLC
3:05 PM
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Skin Cancer and the Solar Cycle: An Application of Kolmogorov-Zurbenko Filters
Edward Valachovic, Department of Epidemiology and Biostatistics, State University of New York at Albany; Igor Zurbenko, State University of New York at Albany
3:20 PM
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Estimate of Search Method Coherence by Using Repeated Probes on Tiled Microarrays
Sigrún Helga Lund, University of Iceland; Gunnar Stefansson, University of Iceland; Thorunn Rafnar, Decode; Daniel Gudbjartsson, Decode
4:05 PM
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Prediction of Tumor Subtypes by Mixture Modeling of Somatic Mutation Profiles
Lin Hou, Yale School of Public Health; Hongyu Zhao, Yale University
4:05 PM
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Multistate Analysis of Interval-Censored Longitudinal Data for Examining Transitions in Performance Status Among Cancer Outpatients
Rinku Sutradhar, Institute for Clinical Evaluative Sciences
4:35 PM
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Bayesian Spatio-Temporal Disease Mapping and Projection Using Data from the National Program of Cancer Registries Lung and Bronchus Cancer 1998--2005
Qiang Ling
5:35 PM
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Monday, 08/05/2013
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Addressing Within-Subject Genomic Heterogeneity
Matthew Nicholson McCall, University of Rochester Medical Center; Anthony Almudevar, University of Rochester Medical Center
8:40 AM
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Excess Lung Cancer Risk Attributable to Low-Dose CT Screening Among Long-Term Smokers
Rui Yang, Quintiles; Deborah Goldwasser, Rice Univeristy
9:00 AM
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Challenges in Age-Period-Cohort Modeling of Breast Cancer Incidence
Ronald Gangnon, University of Wisconsin; Brian Sprague, University of Vermont; Natasha Stout, Harvard Medical School and Harvard Pilgrim Health Care; Oguzhan Alagoz, University of Wisconsin; Amy Trentham-Dietz, University of Wisconsin
9:05 AM
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Discordance in Estrogen Receptor Status Between Two Primary Breast Cancers: Impact of Misclassification
Juxin Liu, University of Saskatchewan; Paul Gustafson, University of British Columbia; Dezheng Huo, The University of Chicago
9:35 AM
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Tumor Dynamics and Central-Review Bias in Progression-Free Survival Clinical Trials
Jonathan Siegel, Bayer HealthCare Pharmaceuticals
11:05 AM
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Time-to-Event Surrogate Endpoint Predicting Overall Survival
Susan Halabi, Duke University; Chen-Yen Lin, Duke University
11:50 AM
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Statistical Analysis of Methylation Array Data
Brooke Fridley, University of Kansas Medical Center
2:05 PM
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A New Marginal Approach to Model Clustered Survival Data with a Cure Fraction
Yingwei Peng, Queen's University; Yi Niu, Queen's University
2:20 PM
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Multistate Models for the Evaluation of Screening Interventions in Family Designs
Laurent Briollais, Samuel Lunenfeld Research Institute; Yun-Hee Choi, Western University; Yildiz Yilmaz, University of Toronto
2:20 PM
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A Semiparametric Model of Personal Cure
Margaret Stedman, National Cancer Institute; Joanne Chang, National Cancer Institute; Kathleen Cronin, National Cancer Institute; Angela Mariotto, National Cancer Institute
2:35 PM
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FDA and Innovative Designs: Case Study of a Missed Opportunity
Andre Rogatko, Samuel Oschin Comprehensive Cancer Institute At Cedars-Sinai Medical Center; Galen Cook-Wiens, Cedars Sinai Medical Center; Mourad Tighiouart, Cedars Sinai Medical Center
2:45 PM
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A Frailty-Based Progressive Multistate Model for Progression and Death in Cancer Studies
Chen Hu, American College of Radiology; Alex Tsodikov, University of Michigan
3:05 PM
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Tuesday, 08/06/2013
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Using Bayesian Hierarchical Model to Detect Related Multiple SNPs Within Multiple Genes to Disease Risk
Lewei Duan
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Model-Based Classifications of High-Throughput Data Review, Design, and Application to a Cancer Clinical Study
AC Cambon, Department of Bioinformatics and Biostatistics, University of Louisville; Shesh Nath Rai, University of Louisville
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Methods to Compare the Myeloproliferative Neoplasm Symptom Assessment Form (MPN-SAF) Across Nine Linguistic Translations
Amylou Dueck, Mayo Clinic; Jeff Sloan, Mayo Clinic; Ruben Mesa, Mayo Clinic
8:40 AM
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Extension of Interval Design to Finding Maximum Tolerated Combinations of Two Anti-Cancer Agents
Lixin Han, Pfizer; Stephanie Green, Pfizer
9:05 AM
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Spatial Analysis of Environmental Risk in Cancer Case-Control Studies with Residential Histories
David Wheeler, Virginia Commonwealth University; Catherine A. Calder, Ohio State University; Kevin Donges, The Ohio State University
9:15 AM
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Optimizing the Choice of Maximum Spatial Window Size in Spatial Scan Statistic
Li Zhu, National Cancer Institute; Junhee Han, Unversity of Arkansas
9:55 AM
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Analysis of Left-Censored Multiplex Immunoassay Data: A Unified Approach
Elizabeth Hill, Medical University of South Carolina; Elizabeth Slate, Florida State University
10:10 AM
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Within Subject Nested Clinical Trial Laboratory Data:Sample Size, Components of Variance and Cost
Borko Jovanovic, Northwestern Univ-Feinberg School of Medicine; Hariharan Subramanian, Northwestern University; Irene Helenowski, Northwestern University ; Alfred Rademaker, Northwestern University; Angela Fought, Northwestern University; Hemant Roy, Northwestern University ; Vadim Backman , Northwestern University
10:35 AM
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Derivatives of Raman Spectra for Breast Cancer Diagnosis
Richard Charnigo, University of Kentucky; Jing Guo, University of Kentucky; Cidambi Srinivasan, University of Kentucky; Ramachandra Dasari, Massachusetts Institute of Technology; Maryann Fitzmaurice, Case Western Reserve University; Abigail Haka, Cornell University
10:50 AM
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Macrolevel Discriminant Analysis: An Extension of Linear Discriminant Analysis for Nested Data
Jose-Miguel Yamal, UT School of Public Health; E. Neely Atkinson, UT MD Anderson Cancer Center; Getie Zewdie, UT School of Public Health; Dennis Cox, Rice University
10:50 AM
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An Algorithm for Binary and Multi-Class Cancer Classification and Informative Genes Selection
Haiyan Wang, Kansas State University
11:20 AM
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Efficient Outlier Identification in Lung Cancer Study
Shibing Deng, Pfizer, Inc.
11:35 AM
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Identifying Epigenomic Biomarkers for Anticancer Drug Responses by Integrating Gene Expression and DNA Methylation Profiles
Zhibao Mi, VA; Kui Shen, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh; Nan Song, the NSABP Foundation, Inc.
12:15 PM
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Questions in Cancer Research: What Are the Most Pressing Statistical Problems?
Gary L. Rosner, Johns Hopkins; Ross Prentice, Fred Hutchinson Cancer Research Center; Kim-Ahn Do, MD Anderson Cancer Center; Bradley McIntosh Broom, MD Anderson
2:05 PM
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Finding the Biologically Optimal Dose with Early Efficacy Biomarkers in Phase I Cancer Clinical Trials
Rui Qin, Mayo Clinic
2:25 PM
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Survival Trees and Forest for Thyroid Cancer Prognostication
Mousumi Banerjee, University of Michigan; Daniel Muenz, University of Michigan; Megan Haymart, University of Michigan
2:45 PM
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A Dose-Escalation Design for Combination Cancer Therapies
Jenny Zhang, Gilead Sciences
2:45 PM
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Predictive Modeling with High-Dimensional Colorimetric Image Data for Lung Cancer Detection
Xiaofeng Wang, Cleveland Clinic Lerner Research Institute; Peter J. Mazzone, Cleveland Clinic Foundation
3:25 PM
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Wednesday, 08/07/2013
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Association Study Between Pelvic Inflammatory Diseases and Colorectal Cancer: Bootstrap Approach
Hui-Wen Lin, Soochow University; Ming-I Hsu, Center of Reproductive Medicine, Wan Fang Hospital
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Pediatric Osteosarcoma and the Stages of Puberty
Rachel Fonstad, University of Minnesota; Logan Spector, University of Minnesota
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Bayesian Segmentation of Cancer Genomes: A Decision Theoretic Approach
Chris Holmes, Oxford University
8:35 AM
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Modeling the Roll-Out of a Bowel Cancer Screening Program
Robert A. Dunne, CSIRO; Lawrence LaPointe, Clinical Genomics
8:35 AM
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Overdiagnosis in Breast and Prostate Cancer Screening: Concepts, Methods, and Mistakes
Ruth Etzioni, Fred Hutchinson Cancer Research Center; Roman Gulati, Fred Hutchinson Cancer Research Center; Leslie Mallinger, Fred Hutchinson Cancer Research Center; Jeanne Mandelblatt, Georgetown University
8:35 AM
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Cost-Effectiveness Analysis of Breast Cancer Screening Strategies
Yu Shen, UT M D Anderson Cancer Center
9:00 AM
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Gene Expression Deconvolution in Heterogenous Tumor Samples
Wenyi Wang, UT MD Anderson Cancer Center
9:00 AM
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Statistical Method and Design: Identify the Subgroups Who Would Have Nontrivial Overall Benefit in the National Lung Screening Trial (NLST)
Ping Hu, Division of Cancer Prevention, National Cancer Institute
9:00 AM
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Statistical Methods in Micro-Simulation Modeling: Calibration and Predictive Accuracy of an MSM for Lung Cancer
Stavroula Chrysanthopoulou, Brown University
9:00 AM
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A Cautionary Note on the Use of a Common ICC in the Analysis of a Two-Arm Cluster Randomized Trial for Cancer Prevention Studies
Sheng Wu, UCLA; Catherine Crespi, UCLA; Weng Kee Wong, Department of Biostatistics, UCLA
9:05 AM
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Joint Analysis of Progression and Survival with Missing Data from a Cancer Clinical Trial
Dianne Finkelstein, MGH and Harvard University; David A Schoenfeld, MGH and Harvard University
9:15 AM
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Measuring the Mortality Reductions Produced by Cancer Screening
James A. Hanley, McGill University; Zhihui(Amy) Liu, McGill University; Erin Strumpf, McGill University; Nandini Dendukuri, McGill University
9:25 AM
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Assessing Uncertainty in Microsimulation Model Projections
Michael Wolfson, University of Ottawa
9:50 AM
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The Use of Risk Models in Disease Prevention
Mitchell Gail, National Cancer Institute
9:50 AM
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Using Tumor Mutational Profiles to Infer Etiologic Heterogeneity of Cancers
Colin B. Begg, Memorial Sloan-Kettering Cancer Center
10:35 AM
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Using RNA-Seq Data to Study the Genetic Basis of Cancer Development
Wei Sun, UNC Chapel Hill; Yun Li, The University of North Carolina; Charles Perou, UNC Chapel Hill
10:35 AM
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Inferring the Chromosomal Landscape of the First Few Cell Divisions in Colorectal Adenomas
Kimberly D Siegmund, University of Southern California; Paul Marjoram, University of Southern California; Darryl Shibata, University of Southern California
11:05 AM
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Estimation of the Optimal Regime in Treatment of Prostate Cancer Recurrence from Observational Data Using Flexible Weighting Models
Jincheng Shen, University of Michigan; Lu Wang, Univeristy of Michigan; Jeremy Taylor, University of Michigan
11:50 AM
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Integrative Analysis and Systems Biology Approaches for Cancer Predictive Signatures
Yang Xie, The University of Texas Southwestern Medical Center; Hao Tang, UT Southwestern Medical Center; Guanghua Xiao, UT Southwestern Medical Center; John Minna, UT Southwestern Medical Center; Ignacio Wistuba, UT MD Anderson Cancer Center
2:05 PM
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Inference for Survival Prediction in the High-Dimensional Setting
Jennifer Sinnott, Harvard University; Tianxi Cai, Harvard University
2:20 PM
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Timing Chromosomal Abnormalities Using Mutation Data
Elizabeth Purdom, UC, Berkeley
2:30 PM
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A Simulation Study of the Effect of Study Duration on Modeling Environmental Risk of Cancer
Kevin Donges, The Ohio State University; Catherine A. Calder, Ohio State University; David Wheeler, Virginia Commonwealth University
2:50 PM
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Improved Performance Evaluation of DNA Copy Number Analysis Methods in Cancer Studies
Pierre Neuvial, CNRS
2:55 PM
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