|
Sunday, 08/01/2010
|
The Use and Misuse of Statistical Methods Reported in Clinical Cancer Research
Diane Liu, MD Anderson Cancer Center; J. Jack Lee, MD Anderson Cancer Center
2:20 PM
|
A Bayesian Surveillance System for Detecting Clusters of Noninfectious Diseases
Albert Y. Kim, University of Washington
2:35 PM
|
Evaluation of Dose-Finding Designs: On the Interplay Between Theory and Simulation
Assaf P. Oron, University of Washington; Peter Hoff, University of Washington
3:05 PM
|
A Single Test Derived from Modeling Biological Heterogeneity of Multiple Serum Biomarkers via Mixture Models Using Bayesian Inference
Eric A. Macklin, MGH Biostatistics Center; Ying Zhou, MGH Biostatistics Center; Trenton C. Pulsipher, MGH Biostatistics Center; Steven James Skates, Massachusetts General Hospital
3:05 PM
|
Phase I Studies: Goals, Patient Selection, and Implications for Design
Paul H. Frankel, City of Hope; Stephen Shibata, City of Hope; Susan Groshen, University of Southern California, Norris; Jeffrey Longmate, City of Hope; Stella Khoo, City of Hope; Edward Newman, City of Hope
4:05 PM
|
Parametric and Nonparametric Survival Analysis of Cancer Data
Bong-Jin Choi, University of South Florida; Chris P. Tsokos, University of South Florida
4:20 PM
|
Determination of Optimal Cut Point for Competing Risks Data
Jeong Youn Lim, University of Pittsburgh; Jong-Hyeon Jeong, University of Pittsburgh
4:35 PM
|
A Projection of True-early-detection, No-early-detection, Overdiagnosis and Not-so-necessary Probabilities in Tumor Screening
Dongfeng Wu, University of Louisville; Gary L. Rosner, MD Anderson Cancer Center
5:25 PM
|
|
Monday, 08/02/2010
|
Interactive Effects of Alcohol and Tobacco on Head and Neck Cancer: A Visualization Using Bivariate Splines
Jennifer JinJin Clark, The University of North Carolina at Chapel Hill; Andrew Olshan, The University of North Carolina at Chapel Hill; Amy H. Herring, The University of North Carolina at Chapel Hill
|
Cancer Marker Identification via Penalized Integrative Analysis
Shuangge Ma, Yale University
|
Logistic Regression with Markov Chains as Covariates with Application in Identifying Lung Cancer Risk Factors
Chung-Han Ho, The University of Texas School of Public Health; Carol J. Etzel, MD Anderson Cancer Center; Wenyaw Chan, The University of Texas School of Public Health; Randa El-Zein, MD Anderson Cancer Center; Alanna C. Morrison, The University of Texas School of Public Health
|
Estimating Average Annual Percent Change in Trend Analysis
Lin Clegg, Department of Veterans Affairs; Ram C. Tiwari, FDA; Rocky Feuer, National Cancer Institute; Brenda Edwards, National Cancer Institute
|
Combining Molecularly Targeted Agents in Cancer Therapy
Eunice Kwak, Massachusetts General Hospital Cancer Center
8:35 AM
|
The Zero-Truncated Poisson Model with Right Censoring: An Application to Translational Breast Cancer Research
Hung-Wen Yeh, The University of Kansas Medical Center; Purna Mukhopadhyay, The University of Kansas Medical Center; Fariba Behbod, The University of Kansas Medical Center; Byron J. Gajewski, The University of Kansas
8:50 AM
|
Simpson's Paradox: Aggregating and Partitioning Populations in Health Care Disparities of Lung Cancer Patients
Pingfu Fu, Case Western Reserve University; Mark Schluchter, Case Western Reserve University; Rom Leidner, Case Western Reserve University; Balazs Halmos, Columbia University Medical Center
9:05 AM
|
More Efficient Experimental Designs for CNV Studies Utilizing aCGH Technology
Jeanette Eckel-Passow, Mayo Clinic; Shannon McDonnell, Mayo Clinic; Shaun Riska, Mayo Clinic; Erik Thorland, Mayo Clinic; Eric Klee, Mayo Clinic
9:05 AM
|
EWOC Online: A Novel Web Application for Computing a Bayesian Phase I Design Method for Dose-Finding with Escalation with Overdose Control
Dror Berel, Cedars-Sinai Medical Center; Andre Rogatko, Oschin Comprehensive Cancer Institute
9:35 AM
|
Clinical Trial Designs for Predictive Biomarker Validation: Theoretical Considerations and Practical Challenges
Daniel Sargent, Mayo Clinic; Sumithra Mandrekar, Mayo Clinic
10:35 AM
|
A Case Study of Using a Genomic Assay to Predict the Benefit of Chemotherapy in Treating Breast Cancer: Testing, Prediction, and Study Planning
William E. Barlow, Cancer Research and Biostatistics (CRAB); Carl Yoshizawa, Genomic Health, Inc.
11:00 AM
|
Comparing the Cumulative False-Positive Risk of Screening Mammography Programs Using a Discrete Time Survival Model Allowing for Nonignorable Drop-Out
Rebecca Hubbard, Group Health Research Institute; Diana Miglioretti, Group Health Research Institute
11:05 AM
|
A Bayesian Model for Misclassified Binary Outcomes and Correlated Survival Data, with Applications to Breast Cancer
Min Yi, The University of Texas Health Science Center at Houston; Sheng Luo, The University of Texas School of Public Health; Xuelin Huang, MD Anderson Cancer Center; Kelly K. Hunt, MD Anderson Cancer Center
11:15 AM
|
Semiparametric Regression Inference for Tumor Progression in Cancer Studies
Chen Hu, University of Michigan; Alexander Tsodikov, University of Michigan
11:20 AM
|
Statistical Analysis of Somatic Changes in Cancer Genomics
Giovanni Parmigiani, Harvard University
11:25 AM
|
Feature Selection for Censored Outcomes with Simultaneous Adjustment for Nonlinear Covariate Effect and Improved Risk Scores of Prostate Cancer Recurrence
Qi Long, Emory University; Brent Johnson, Emory University; Carlos S. Moreno, Emory University
11:35 AM
|
A Bayesian Shrinkage Model for Incomplete Longitudinal Binary Data with Application to the Breast Cancer Prevention Trial
Chenguang Wang, FDA; Michael J. Daniels, University of Florida; Daniel O. Scharfstein, Johns Hopkins Bloomberg School of Public Health; Stephanie R. Land, University of Pittsburgh
11:35 AM
|
Novel Methodologies for Gene Network Interaction Analysis and Network Modeling with Applications to Cancer Research and Cardiovascular Disease
Bala Rajaratnam, Stanford University; Sang-Yun Oh, Stanford University
11:50 AM
|
A Joint Model of Longitudinal Data and Time-to-Event Data with Cure Fraction
Ashok Panneerselvam, Case Western Reserve University; Mark Schluchter, Case Western Reserve University
2:05 PM
|
Bayesian Inference for Stereotype Regression
Bhramar Mukherjee, University of Michigan
2:25 PM
|
Semiparametric Bayesian Analysis of High-Throughput Array CGH Data
Subharup Guha, University of Missouri
2:35 PM
|
Method and Application of Meta-Analysis in Cancer Trials
Xiaoling Wu, Bristol-Myers Squibb; Joseph Pultz, Bristol-Myers Squibb; Andrew Damokosh, Bristol-Myers Squibb; Thomas Kelleher, Bristol-Myers Squibb
2:35 PM
|
Understanding Diffusion of Innovative Treatments for Kidney Cancer Using Trees
Mousumi Banerjee, University of Michigan
3:05 PM
|
Whole-Genome Sequence of a Multiplex Lung Cancer Family by Using Next-Generation Sequencer
Hsuan-Yu Chen, Academia Sinica; Ker-Chau Li, Academia Sinica; Sung-Liang Yu, National Taiwan University; Jeremy J. W. Chen, National Chung Hsing University; Pan-Chyr Yang, National Taiwan University
3:20 PM
|
A Review of Statistical Methods for Testing Genetic Anticipation: Looking for an Answer in Lynch Syndrome
Philip Boonstra, University of Michigan; Bhramar Mukherjee, University of Michigan; Stephen Gruber, University of Michigan
3:20 PM
|
|
Tuesday, 08/03/2010
|
High Dimentional ROC Analysis Can Improve the Correlation Between Histological Grade (HG) and Oncotype-Dx (ONC) Recurrence Risk (RR) in Breast Cancer (BC)
Yufeng Li, The University of Alabama at Birmingham; Choo Hyung Lee, The University of Alabama at Birmingham; Omar Hameed, The University of Alabama at Birmingham
|
Bayesian Methods for Copy Number Inference in Heterogeneous Cancers Using SNP Arrays
Christopher Yau, University of Oxford; Christopher C. Holmes, University of Oxford
|
Design, Implementation, and Results for a Bayesian Adaptive Randomization Trial for Targeted Therapy in Lung Cancer
Suyu Liu, MD Anderson Cancer Center; J. Jack Lee, MD Anderson Cancer Center
|
A Comparison of Change Point Methods for Lymph Node Risk Factors in Three Cancers
Marianne Huebner, Mayo Clinic; Rui Qin, Mayo Clinic
|
Instrument Variable Analysis of Prostate Cancer Treatments for Clustered Binary Data
Anjun Cao, NovoNordisk; Dirk F. Moore, University of Medicine and Dentistry of New Jersey
|
Statistical Models for Adenoma Data from Colorectal Polyp Prevention Trials
Chiu-Hsieh Hsu, The University of Arizona; Sadhvi Khanna, The University of Arizona
|
Discovering Influential Variables: A Partition-Based Learning Method to Identify Susceptible Genetic Risk Factors in Common Human Disorders
Tian Zheng, Columbia University; Herman Chernoff, Harvard University; Shaw-Hwa Lo, Columbia University
8:35 AM
|
Estimating Reduction in Absolute Breast Cancer Risk in Individuals and Populations from Modifying Risk Factors
Elisabetta Petracci, Institute of Medical Statistics and Biometry ; Adriano Decarli, Institute of Medical Statistics and Biometry ; Domenico Palli, Scientific Institute of Tuscany; Giovanna Masala, Scientific Institute of Tuscany; David Pee, Information Management Service Inc.; Ruth Pfeiffer, National Cancer Institute; Catherine Schairer, Division of Cancer Epidemiology and Genetics; Mitchell H. Gail, National Cancer Institute
8:50 AM
|
Personalized Medicine Trials in Non-Small Cell Lung Cancer
Michael Kosorok, The University of North Carolina at Chapel Hill; Yufan Zhao, Amgen Inc.; Donglin Zeng, The University of North Carolina at Chapel Hill; Mark Socinski, The University of North Carolina at Chapel Hill
9:00 AM
|
Estimating Colorectal Cancer Screening in the Presence of Missing Data in a Population with a Resistant Subset and Multiple Observations
Yolanda Cecile Hagar, University of California, Davis; Laurel Beckett, University of California, Davis; Danielle Harvey, University of California, Davis School of Medicine; Joshua Fenton, University of California, Davis School of Medicine
9:05 AM
|
An Assessment of Quality of Life Among Breast Cancer Survivors in Punjab Using Ordinal Regression
Shahid Kamal, University of the Punjab; Ghausia Masood Gilani, University of the Punjab; Rehan Ahmad Khan, University of the Punjab; Afza Rasul, University of the Punjab
9:20 AM
|
BMI, Alcohol, Prostate Cancer, and Mortality Follow-Up
Negasi T. Beyene, CDC; Peter Meyer, National Center for Health Statistics
9:50 AM
|
Calibrating Microsimulations with Multicriteria Optimization Algorithms
Chung Yin Kong, Massachusetts General Hospital
10:35 AM
|
Classification of Cancer Microarrays by v-Ridge Regression
June Luo, Clemson University
10:35 AM
|
The Interplay Between Body Mass Index, Prostate-Specific Antigen, and Prostate Cancer Risk
Yuanyuan Liang, The University of Texas Health Science Center at San Antonio; Donna Pauler Ankerst, Technical University; Michael Sanchez, The University of Texas at San Antonio; Robin J. Leach, The University of Texas Health Science Center at San Antonio; Ian Murchie Thompson, The University of Texas Health Science Center at San Antonio
10:35 AM
|
Reference Priors for Constrained Poisson Models
Michael David Sonksen, The Ohio State University; Mario Peruggia, The Ohio State University
10:35 AM
|
I-SPY2: Identifying Biomarker Signatures for Therapeutic Agents in Neoadjuvant Breast Cancer
Donald Arthur Berry, MD Anderson Cancer Center; Kyle Wathen, MD Anderson Cancer Center; Nebiyou Bekele, MD Anderson Cancer Center; Laura Esserman, University of California, San Francisco
11:35 AM
|
Genes Selection and Components Retention for Supervised Survival Prediction Models
Keyue Ding, Queen's University
2:05 PM
|
The Role of Proxy Genes in Predictive Models: An Application to Early Detection of Prostate Cancer
Jay Magidson, Statistical Innovations Inc.; William Oh, Mount Sinai School of Medicine; Robert Ross, Infinity Pharmaceuticals; Philip Kantoff, Dana-Farber Cancer Institute; Karl Wassmann, Source MDx
2:20 PM
|
Benchmark Dose Estimation in Environmental Risk Assessment: From Cancer to Genetic Toxicity and Beyond
Walter W. Piegorsch, The University of Arizona
3:20 PM
|
An Extended Propensity Score Approach for the Analysis of Population-Based Genetic Association Studies
Huaqing Zhao, University of Pennsylvania School of Medicine; Timothy R. Rebbeck, University of Pennsylvania School of Medicine; Nandita Mitra, University of Pennsylvania School of Medicine
3:20 PM
|
|
Wednesday, 08/04/2010
|
A Statistician at the Policy Table: Integrating Modeling in the Development of Public Health Guidelines
Ruth Etzioni, Fred Hutchinson Cancer Research Center
|
Phase I Dose-Finding in Cancer Trials Based on a Discrete Time Multistate Model
Lin Yang, MD Anderson Cancer Center; Nebiyou Bekele, MD Anderson Cancer Center; Donald Arthur Berry, MD Anderson Cancer Center
8:50 AM
|
Combining Information on Adjuvant Cancer Therapies from Multiple Sources to Correct Misreporting
Yulei He, Harvard Medical School; Alan Zaslavsky, Harvard Medical School
9:05 AM
|
Empirical Evaluation of Methods for Predicting Cancer Incidence and Mortality in Canada
Michael Otterstatter, Public Health Agency of Canada; Lin Xie, Public Health Agency of Canada
10:35 AM
|
Mutation Rate Estimation and Classification of Driver and Passenger Genes in Cancer
Jie Ding, Dana-Farber Cancer Institute; Giovanni Parmigiani, Harvard University; Xiaogang Zhong, The Johns Hopkins University
10:35 AM
|
Statistical Inference in Factor Analysis for High-Dimension, Low-Sample-Size Data
Miguel Marino, Harvard University/Dana-Farber Cancer Institute; Yi Li, Harvard University/Dana-Farber Cancer Institute
10:50 AM
|
Cancer Risk in the Environment: Public Policy Issues in Screening
Karen Kafadar, Indiana University; Philip Prorok, National Cancer Institute
11:05 AM
|
MicroRNA-Guided Gene Classifier in Colorectal Cancer
Dung-Tsa Chen, Moffitt Cancer Center & Research Institute; Timothy Yeatman, Moffitt Cancer Center & Research Institute; William Fulp, Moffitt Cancer Center & Research Institute; Mike Gruidl, Moffitt Cancer Center & Research Institute
11:20 AM
|
Bayesian Semiparametric Models for Testing Single and Multiple Genetic Pathway Effects in Prostate Cancer
Sounak Chakraborty, University of Missouri-Columbia
11:50 AM
|
Calling Hits in a High-Throughput Screening Assay
Minya Pu, University of California, San Diego; Karen Messer, University of California, San Diego
12:05 PM
|
Hierarchical Gaussian Power Prior Models for Adaptive Incorporation of Historical Information in Clinical Trials
Bradley P. Carlin, University of Minnesota; Brian P. Hobbs, University of Minnesota; Daniel Sargent, Mayo Clinic; Sumithra Mandrekar, Mayo Clinic
2:05 PM
|
Sequential Design of Phase II--III Cancer Trials
Tze Leung Lai, Stanford University; Philip Lavori, Stanford University; Mei-Chiung Shih, Stanford University
2:05 PM
|
Nonparametric Estimation of Concordance Probability with Censored Data
Mithat Gonen, Memorial Sloan-Kettering Cancer Center; Glenn Heller, Memorial Sloan-Kettering Cancer Center; Qianxing Mo, Memorial Sloan-Kettering Cancer Center
2:45 PM
|
Estimating Cost of Treatment in Elderly Patients with Colorectal Cancer Using Medicare Data
Emma Boswell, Trinity Partners, Inc.; Fotios K. Kokkotos, Trinity Partners, Inc.; Xiulin Shen, Trinity Partners, Inc.; Zheng Wang, Trinity Partners, Inc.; Ya Zhang, Trinity Partners, Inc.
2:50 PM
|
Predictive Probability Approach for the Design and Analysis of Response and Toxicity Data in Cancer Clinical Trials
J. Jack Lee, MD Anderson Cancer Center; Guosheng Yin, The University of Hong Kong; Nan Chen, M D Anderson Cancer Center
2:55 PM
|
|
Thursday, 08/05/2010
|
Risk Models for Deciding Whether to Take Tamoxifen to Prevent Breast Cancer and for Allocating Public Health Resources
Mitchell H. Gail, National Cancer Institute
8:35 AM
|
On the Ability of Breast Cancer-Associated SNPs to Augment Clinical Variables in Predicting Breast Cancer Risk
Ross L. Prentice, Fred Hutchinson Cancer Research Center; David A. Hinds, Perlegen Sciences
8:35 AM
|
Study Designs for Evaluating Personal Risk Models
Alice S. Whittemore, Stanford University
9:05 AM
|
Comparing Statistical Models Used in Analysis of a Discrete Choice Experiment
Ji Cheng, St. Joseph's Healthcare Hamilton; Lehana Thabane, McMaster University; Deborah Marshall, University of Calgary; John K. Marshall , McMaster University
10:35 AM
|
The Use of Nomogram Predictions as Comparators for Adjuvant Treatment Studies in Prostate Cancer
Zhenyu Jia, University of California, Irvine; James Koziol, The Scripps Research Institute; Michael Lilly, University of California, Irvine; Dan Mercola, University of California, Irvine
11:05 AM
|
Residential Mobility, Cancer and Local Indicators of Geocoding Accuracy
Geoffrey Mark Jacquez, TerraSeer; Robert Rommel, TerraSeer
11:15 AM
|
A CAR Model on Quality of Life of Breast Cancer Survivors with Application of an Ancillarity Sufficiency Interweaving Scheme
Yajun Liu, University of Missouri
11:35 AM
|
Identification of Protein Phosphorylation Sites Using Zero-Inflated Poisson Regression
Shu Yang, Boston University; Eric Kolaczyk, Boston University; Simon Kasif, Boston University; Martin Steffen, Boston University
11:35 AM
|
|