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Sunday, 08/01/2010
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Large-Scale Simulation Evaluation for Model Selection: Lasso and Bayesian Derivatives
Alan Burton Lenarcic, Harvard University; Edoardo M. Airoldi, Harvard University; Palak Patel, Harvard University
2:20 PM
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Evaluation of Dose-Finding Designs: On the Interplay Between Theory and Simulation
Assaf P. Oron, University of Washington; Peter Hoff, University of Washington
3:05 PM
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Design and Analysis of a Simulation Study on MPLS Network
Wenbiao Zhang, Insurance Corporation of British Columbia; Pranesh Kumar, University of Northern British Columbia
3:05 PM
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Comparing Methods of Estimating Treatment Effects on a Continuous Outcome in Multicenter Randomized Controlled Trials: A Simulation Study
Rong Chu, McMaster University; Lehana Thabane, McMaster University; Jinhui Ma, McMaster University; Eleanor Pullenayegum , McMaster University; Anne Holbrook, McMaster University
3:20 PM
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Visualizing and Finding Minimum Delay Flights
Tanujit Dey, The College of William & Mary; David Phillips, The College of William & Mary; Patrick Steele, The College of William & Mary
3:25 PM
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Bayesian Adaptive Designs for Dose Escalation Studies
Anna Elizabeth McGlothlin, Eli Lilly and Company
4:05 PM
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Modeling the Dynamics of Corporate Credit Ratings: Estimating Ratings Transitions
Terri Anna Johnson, North Carolina State University; Meghan Rachel Kent, North Carolina State University
4:20 PM
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Inference on Treatment Effect Under a Density Ratio Model and Random Censoring
Shan Jiang, Queen's University; Dongsheng Tu, Queen's University
4:20 PM
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Simulation of Risk of Codling Moth Establishment from Imported Apples
Eleanor Shannon Neeley, Brigham Young University
4:20 PM
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Two-Stage Adaptive Design for Bioequivalence: Methods and Application
Yi-Lin Chiu, Abbott Global Pharmaceuticals Research and Development; Yannis Jemiai, Cytel Inc.; Charles Locke, Abbott Laboratories; Pralay Senchaudhuri, Cytel Inc.
4:25 PM
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Evaluating Prospective Integration of Survey and Administrative Record Data: The Impact of Uncertainty in Measurement of Data Quality and Cost Factors
Randall Powers, Bureau of Labor Statistics; John L. Eltinge, Bureau of Labor Statistics
4:25 PM
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More for Less? Comparing Small-Area Estimation, Spatial Microsimulation, and Mass Imputation
Stephen John Haslett, Massey University; Geoffrey Jones, Massey University; Alasdair Dewar Noble, Massey University; Dimitris Ballas, University of Sheffield
4:50 PM
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A Bayesian Dose-Finding Design Adapting to Efficacy and Tolerability Response
S. Krishna Padmanabhan, Pfizer Inc.; Scott Berry, Berry Consultants, LLC; Vladimir Dragalin, Pfizer Inc.; Michael Krams, Pfizer Inc.
5:05 PM
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Monday, 08/02/2010
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Does Food-Grouping Make a Difference When Deriving Dietary Patterns Using Latent Class Models? A Monte Carlo Simulation Study
Daniela Sotres-Alvarez, The University of North Carolina at Chapel Hill; Amy H. Herring, The University of North Carolina at Chapel Hill; Anna Maria Siega-Riz, The University of North Carolina at Chapel Hill
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A Simulation to Evaluate the Impact of Design on Model-Based Methods for National Health and Nutrition Examination Survey (NHANES) Data Linked with Environmental Exposures
Jennifer Parker, National Center for Health Statistics; Lester Randolph Curtin, CDC; Van Parsons, National Center for Health Statistics
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Simulation of Kidney Paired Donation Programs
Yijiang (John) Li, University of Michigan; Yan Zhou, University of Michigan; John David Kalbfleisch, University of Michigan; Peter Song, University of Michigan
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Classroom Derivation and Simulation: An Asymptotic Two-Sample Test for Comparing Population Medians
Vadim Y. Bichutskiy, California State University, East Bay; Joshua D. Kerr, California State University, East Bay; Eric A. Suess, California State University, East Bay
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Generic Framework for Parallel Statistical Computing
Hana Sevcikova, University of Washington
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A Simulation Study to Evaluate Dose-Response in Dose-Titration Clinical Trials: A Dynamic Linear Mixed Effect (DLME) Modeling Approach
Xu Steven Xu, Johnson & Johnson; Min Yuan, Fudan University, China; Julia Wang, Johnson & Johnson; Partha Nandy, Johnson & Johnson
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Issues of Data Capacity and Statistical Quality to Support Health Care Modeling and Microsimulation Efforts
Joel Cohen, AHRQ
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Modeling and Inference for Interaction Processes for Unions of Discs
Jesper Møller, Aalborg University
8:35 AM
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Confounding Bias Correction for Longitudinal Data
Yuanzhang Li, Walter Reed Army Institute of Research ; Robert Yolken, Johns Hopkins School of Medicine; David Niebuhr, Walter Reed Army Institute of Research
9:05 AM
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Modeling and Simulation of Survey Collection Using Paradata
Kristen Couture, Statistics Canada; Elisabeth Neusy, Statistics Canada; Yves Bélanger, Statistics Canada
9:35 AM
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Q Charts for the Exponential Distribution
Schalk William Human, University of Pretoria; Subhabrata Chakraborti, The University of Alabama
11:50 AM
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Sample Size Estimates for Correlated Data in a Device Trial
Xiaolong Shih, Boston Scientific Corporation
2:25 PM
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On the Effect of Diagnostic Misclassification Bias on the Observed Spatial Pattern in Regional Count Data: A Simulation Study
Olaf Berke, University of Guelph
2:35 PM
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Assessing the Impact of Partial Monitoring on Power Within Clinical Trials
Joe William Bero, Boston Scientific Corporation
2:45 PM
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Using Copula Methods to Create Synthetic Data Sets for Agricultural Applications
Timothy Paul Keller, National Agricultural Statistics Service; Darcy Miller, National Agricultural Statistics Service
3:05 PM
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Overcoming the Winner's Curse to Identify Biomarkers with Clinical Relevance in Drug Development
Lei Shen, Eli Lilly and Company; Haoda Fu, Eli Lilly and Company
3:20 PM
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Finiteness Matters in Inference for New Keynesian Phillips Curve
Hrishikesh (Rick) D. Vinod, Fordham University
3:20 PM
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Tuesday, 08/03/2010
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Has the Housing Market Hit Bottom?
Kristen Elizabeth Gulledge, North Carolina State University; Emily Wisner, North Carolina State University
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On the Modeling and Simulation of Ambulatory Blood Pressure Traces
David A. James, Novartis; Xiaoyong Sun, Iowa State University
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Power in the Case of Extreme Bimodal Distribution: Analysis of Delirium/Coma-Free Days in the ICU
Jennifer L. Thompson, Vanderbilt University; Ayumi Shintani, Vanderbilt University
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Sample-Size Estimation for the Interaction Between Two Binary Covariates in a Cox Proportional Hazard Regression Model
Abu Minhajuddin, The University of Texas Southwestern Medical Center at Dallas; Xian-Jin Xie, The University of Texas Southwestern Medical Center at Dallas
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Remarks on the Test of Multivariate Normality by Union Intersection Principle
Chun-Chao Wang, National Taipei University; Yi-Ting Hwang, National Taipei University
8:50 AM
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Calibrating Microsimulations with Multicriteria Optimization Algorithms
Chung Yin Kong, Massachusetts General Hospital
10:35 AM
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Regenerative Simulation for Variable-at-a-Time Metropolis-Hastings Algorithms
Ronald Charles Neath, Baruch College, CUNY; Galin L. Jones, University of Minnesota
10:35 AM
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Improved Estimates for the Impact of Baserunning in Baseball
Benjamin Strong Baumer, CUNY Graduate Center
10:55 AM
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Scaled Average Bioequivalence for Highly Variable Drugs
Scott Patterson, Pfizer Inc.; Byron Jones, Pfizer Inc.; Dieter Hauschke, University Medical Center Freiburg
10:55 AM
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A Quadratic Regression Approach to Maximize the Mean Simulated Likelihood in Microsimulation Models with Few Parameters
Roman Gulati, Fred Hutchinson Cancer Research Center; Lurdes Inoue, University of Washington; Ruth Etzioni, Fred Hutchinson Cancer Research Center
11:00 AM
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Bayesian Calibration of Microsimulation Models
Carolyn M. Rutter, Group Health Research Institute
11:25 AM
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Shrinkage Nonparametric Estimation of Median Survival Time from Censored Data
Mohammad Hossein Rahbar, The University of Texas Health Science Center at Houston; Weiwei Wang, The University of Texas Health Science Center at Houston; Jing Ning, The University of Texas Health Science Center at Houston
2:05 PM
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Partially Adaptive Estimation of Truncated Regression Models: A Comparison with Several Semiparametric Estimators
Patrick Ansel Turley, Brigham Young University; James B McDonald, Brigham Young University
2:35 PM
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Multi-Agent Simulation
Yasmin H. Said, George Mason University
3:05 PM
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Wednesday, 08/04/2010
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Number of Replications Required in Simulation Studies: A Synthesis of Four Studies
Daniel Mundfrom, New Mexico State University; Jay R. Schaffer, University of Northern Colorado; Myoung-Jin Kim, Illinois State University; Dale Shaw, University of Northern Colorado; Ampai Thongteeraparp, Kasetsart University; Chana Preecha, Thepsatri Rajabhat University; Pornsin Supawan, Rajabhat Rajanagarindra University
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Efficiency of the Search Algorithms
Morteza Marzjarani, Saginaw Valley State University; Stephen Bauer, Saginaw Valley State University; Evan Schultz, Saginaw Valley State University
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The Effect of Weights and Sampling Plans on Price Index Estimates: a Simulation Study
Daniele Toninelli, University of Bergamo; Zdenek Patak, Statistics Canada
8:35 AM
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Statistical Methods for Estimating a Minimum
Shiyao Liu, Iowa State University; William Q. Meeker, Iowa State University
8:35 AM
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Simulating JOLTS Hires and Separations Data Using Historical QCEW Data
Mark Crankshaw, Bureau of Labor Statistics
8:35 AM
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Strategies for Pulling the Goalie in Hockey
David Beaudoin, Universite Laval; Tim B. Swartz, Simon Fraser University
8:50 AM
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Testing Small Center Events in Multicenter Trials Using Survival Modeling
Usha Sita Govindarajulu, Brigham and Women's Hospital, Harvard Medical School; Elizabeth J. Malloy, American University; James Dziura, Yale University
9:05 AM
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Confidence Interval Estimation for Inter-Rater Reliability in a Two-Factor Random-Effects Design
Joseph C. Cappelleri, Pfizer Inc.; Kelly H. Zou, Pfizer Inc.; Carmen Arteaga, Pfizer Inc.; Naitee Ting, Boehringer Ingelheim Pharmaceuticals, Inc.
9:20 AM
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A Simulation-Based Improvement
Thomas H. Taylor, Jr., CDC; Melissa Lewis, CDC; Elizabeth R. Zell, CDC
9:20 AM
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Real-Time Simulation of Alternative Specification of Euro Area Turning Points Detection
Gian Luigi Mazzi, EUROSTAT; Monica Billio, Università di Venezia; Rosa Ruggeri Cannata, EUROSTAT
9:35 AM
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Key Considerations for Simulations to Optimize Dose-Finding Trials
Natalie Cheung Hall, Eli Lilly and Company
10:35 AM
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Further Simulation Results on the Distribution of Some Survey Variance Estimators
Elizabeth T. Huang, U.S. Census Bureau; William R. Bell, U.S. Census Bureau
10:50 AM
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Data-Driven Models for Dynamic Networks in Changing Populations
Pavel N. Krivitsky, Carnegie Mellon University; Mark Stephen Handcock, University of California, Los Angeles; Martina Morris, University of Washington
10:50 AM
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Cancer Risk in the Environment: Public Policy Issues in Screening
Karen Kafadar, Indiana University; Philip Prorok, National Cancer Institute
11:05 AM
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Should I Use Gain Scores to Determine Treatment Effect from a Pretest-Posttest Design?: A Simulation Study
Michael Posner, Villanova University; AnneMichele Millar, Mount Saint Vincent University; Philip Yates, California State Polytechnic University, Pomona
11:15 AM
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Sparse Data in Meta-Analysis: Parametric and Semiparametric Models and Parameterization Issues
Arpita Chatterjee, Northern Illinois University; Sanjib Basu, Northern Illinois University
11:15 AM
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Comparison of Meta-Analytic Methods That Combine Direct and Indirect Evidence to Assess Dose Relationship
Qi Zhang, Eli Lilly and Company; Mary Nilsson, Eli Lilly and Company; Yoko Tanaka, Eli Lilly and Company; Brenda Crowe, Eli Lilly and Company; Xiaobi Huang, University of Michigan
11:20 AM
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Simulation of Incorporating the Variance from Missing Data in Census Coverage Measurement (CCM) Variance Estimates
Richard Griffin, U.S. Census Bureau
11:50 AM
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Simulation of a Phase III Trial Using Realizations of Posterior Distribution Based on a Phase IIb Trial
A. Lawrence Gould, Merck Research Laboratories
2:05 PM
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Adaptive Dose Finding Using the 'Maximizing Procedure': Case Study and Missing Data Simulation
Kenneth Liu, Merck & Co., Inc.
2:25 PM
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Performance of Prediction Measures in a Survival Setting
Nina P. Paynter, Brigham and Women's Hospital; Linda M. Peelen, Julius Center for Health Sciences and Primary Care UMC Utrecht; Nancy Cook, Brigham and Women's Hospital
2:25 PM
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Total Migraine Freedom: A Potential Primary Endpoint to Assess Acute Treatment in Migraine
Anthony J. Rodgers, Merck & Co., Inc.
2:35 PM
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Informed Decisionmaking Using Modeling and Simulation: Case Study of a Selective PDE5 Inhibitor for the Treatment of BPH
Patrick John Johnson, Vifor Pharma Ltd.
2:45 PM
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Studying Student Learning Trajectories for Sampling Distributions by Using Simulation Activities
Aaron Weinberg, Ithaca College; Stacey Hancock, Reed College; Jennifer Noll, Portland State University; Sean Simpson, Westchester Community College
2:45 PM
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Estimation of Odds Ratio with Rare Event Case: A Simulation Study Based on Hospitalized Flu Vaccine Study
Qingxia Chen, Vanderbilt University; Yuwei Zhu, Vanderbilt University; Helen K.B. Talbot, Vanderbilt University; Marie R. Griffin, Vanderbilt University; Kathryn M. Edwards, Vanderbilt University
3:20 PM
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Adding a Prediction Interval Futility Analysis to a Group Sequential Trial
John Loewy, ARIAD Pharmaceuticals; David Dorer, ARIAD Pharmaceuticals
3:25 PM
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Alternative Weight Trimming Methods to Estimate Totals in Single-Stage Sample Designs
Kimberly Henry, IRS
3:25 PM
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Thursday, 08/05/2010
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Adaptive Designs for Dose-Ranging Studies
Vladimir Dragalin, Pfizer Inc.
8:35 AM
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Comparison of Hauer's EB method, Causal Inference Methods, and a Full Bayesian Method for Estimating Countermeasure Effectiveness in Transportation Safety Studies
Courtney Bokenkroger, Midwest Research Institute
8:35 AM
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The Impact of Measurement Error in Auxiliary Variables on Model-Based Estimation of Finite Population Totals: A Simulation Study
Brady West, Institute for Social Research
8:55 AM
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Impact of Missing Data on the Analysis of Crossover Data
Anjela Tzontcheva, Merck & Co., Inc.; Mahtab Marker, Merck & Co., Inc.
9:05 AM
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Some Sources of Bias and Instability in Binary Imputation by Dichotomization of Model-Based Predicted Probabilities: A Simulation-Based Study
Peter Richardson, Houston VA Medical Center/HSR&D
9:15 AM
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Classification of Long Memory Processes: A Simulation Study
Ritaja Sur, University of Maryland; Benjamin Kedem, University of Maryland
9:20 AM
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Finite Sample Properties of Minimum Kolmogorov-Smirnov Estimator and Maximum Likelihood Estimator for Right-Censored Data
Jerzy Wieczorek, U.S. Census Bureau; Jong Sung Kim, Portland State University
9:20 AM
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Simulation Study for Comparison and Evaluation of Differentially Expressed Gene-Detection Methods in mRNA-Seq
Sunghee Oh, Yale University ; Hongyu Zhao, Yale University; James P. Noonan, Yale University
9:20 AM
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Selecting Covariance Structures in 3, 4, and 6 Period PK and PD Crossover Trials
Deborah Panebianco, Merck & Co., Inc.; Tom Bradstreet, Merck & Co., Inc.; Andrea Maes, Novartis Pharmaceuticals Corporation; Lata Maganti, Merck & Co., Inc.
9:20 AM
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Reducing Parameter Estimation Bias for Data with Missing Values Using Simulation Extrapolation
YU-YI Hsu, Iowa State University; Yongming Qu, Eli Lilly and Company; Alicia Carriquiry, Iowa State University
10:35 AM
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CTDesignExplorer: An Action Queue--Based Open-Source Simulation Experiment Platform for Evaluating Clinical Trial Designs
Yuanyuan Wang, University of Pittsburgh; Roger Day, University of Pittsburgh; Daniel Normolle, University of Pittsburgh
10:50 AM
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Simulation for Golf Resort Overbooking
Melvin Ott, Melvin Ott & Associates
10:50 AM
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Approximating High-Dimensional Simulations in Low-Dimensional Space, with Application to Microarray Prediction Error Estimation
Kevin Dobbin, The University of Georgia
10:50 AM
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A Simulation Study on the Effects of Increasing the Number of Capture Periods in Closed Population Capture-Recapture Models with Heterogeneity
Jose Sanqui, Appalachian State University; Ross Gosky, Appalachian State University
10:50 AM
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A Simulation Study to Compare Modeling Approaches for Dose Proportionality Data
Andrea Maes, Novartis Pharmaceuticals Corporation; Wen-Lin Luo, Merck & Co., Inc.; Yu Ding, Merck Research Laboratories; Deborah Panebianco, Merck & Co., Inc.
11:05 AM
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Experience with Using Simulation Models to Plan for Drug Supply in Adaptive Trials
Nitin R. Patel, Cytel Inc.; Suvajit Samanta, Merck Research Laboratories; Pralay Senchaudhuri, Cytel Inc.; Christine Stocklin, Merck & Co., Inc.
11:15 AM
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How to Analyze Ordinal Categorical Data: Some Simulation Results
George Zhang, Daiichi Sankyo Pharma Development
11:20 AM
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A Simulation Study to Evaluate Sample Size and Power for a Trial to Develop a Prediction Rule Using Machine Learning Methods
Radha Railkar, Merck & Co., Inc.; Matthew Wiener, Merck & Co., Inc.; Leonidas Carayannopoulos, Merck & Co., Inc.
11:20 AM
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Simulating the Characteristics of Populations at the Small-Area Level: New Validation Techniques for a Spatial Microsimulation Model in Australia
Azizur Rahman, University of Canberra; Ann Harding, National Centre for Social and Economic Modelling; Robert Tanton, National Centre for Social and Economic Modelling; Shuangzhe Liu, National Centre for Social and Economic Modelling
11:35 AM
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