Sample size re-estimation is a common adaptation in adaptive design trials. Blinded sample size re-estimation for proportions, time-to-event, continous data and count data have been proposed in the literature. Blinded assessments of sample sizes done within the context of internal pilot studies are considered to incur no penalty for inflating the type I error. Despite the attractive feature of not inflating type I error, logistical and scientific considerations may still require that unblinded sample size re-estimation be performed. This roundtable aims to discuss the concepts, and applications of both unblinded and blinded sample size re-estimation with focus on when sample size re-estimation can be recommended and the logistical considerations for mode of re-estimation.