Logistics of Implementing Adaptive Trial Designs and Adaptive Randomizations
*Eva Miller, Almac Group Keywords: Logistical considerations for adaptive trial implementation are more involved requiring more planning, constant communication and greater teamwork than traditional ones. Adaptive studies also require automated systems with inherent flexibility, speed, accuracy, timely results reporting and automated drug supply management. These logistical and operational considerations in implementing adaptive designs have recently drawn greater attention because the infrastructure for managing the traditional double-blind, randomized, parallel group clinical trial does not lend itself to the challenges presented in implementation of flexible designs. A form of adaptive trial design involving the allocation rule (covariate baseline adaptive randomization, response adaptive randomization or hybrids involving both covariate baseline and response adaptive randomization) requires planning, simulations, and
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Key Dates
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April 30 - May 22, 2013
Invited Abstract Submission Open -
June 4, 2013
Online Registration Opens -
August 9 - August 23, 2013
Invited Abstract Editing -
August 23, 2013
Short Course materials due from Instructors -
August 26, 2013
Housing Deadline -
September 9, 2013
Cancellation Deadline and Registration Closes @ 11:59 pm EDT -
September 16 - September 18, 2013
Marriott Wardman Park, Washington, DC