Dose uniformity is one of most critical requirements of pharmaceutical products. Current two-tier procedure is a modification of the USPXXVI sampling plan of dose content uniformity. Due to using a zero tolerance criterion, it has a near-zero probability acceptance at the second tier. Increased risk to manufacturers of unnecessarily rejecting good product may arise from current testing paradigms-zero tolerance criteria, utilizing increased sampling, such as medium and large samples in dose uniformity testing. We propose a two-tier sequential tolerance interval approach, equivalent to a two-tier two one-sided testing procedure, controlling the probability to a product delivering below a pre-specified dose and the probability of a product delivering over a pre-specified dose. When generalizing the test to medium or large sample, the specification reflects the requirement for quality.